Results 21 to 30 of about 18,708 (168)
Urocortins in the mammalian endocrine system
Acta Veterinaria Scandinavica, 2019 Urocortins (Ucns), peptides belonging to the corticotropin-releasing hormone (CRH) family, are classified into Ucn1, Ucn2, and Ucn3. They are involved in regulating several body functions by binding to two G protein-coupled receptors: receptor type 1 ...
Caterina Squillacioti +3 more
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Biomedicines, 2023 The aim of the present study was to determine the effects of alcohol intoxication and withdrawal on hypothalamic neurohormones such as corticotropin-releasing factor (CRF) and arginine vasopressin (AVP), and extrahypothalamic neurotransmitters such as ...
Balázs Simon +9 more
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Frontiers in Molecular Neuroscience, 2018 Based on pharmacological studies, corticotropin-releasing hormone (CRH) and its receptors play a leading role in the inhibition of the hypothalamic–pituitary–gonadal (HPG) axis during acute stress.
Androniki Raftogianni +11 more
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Frontiers in Neuroscience, 2021 The bed nuclei of the stria terminalis (BST) is a limbic region in the extended amygdala that is heavily implicated in anxiety processing and hypothalamic-adrenal-pituitary (HPA) axis activation.
Claire Emily Young +3 more
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Can modulating corticotropin releasing hormone receptors alter visceral sensitivity? [PDF]
Gut, 2006 Activation of corticotropin releasing hormone (CRH) receptor 2 (CRH-R2) reduces visceral sensitivity induced by colorectal distension in conscious rats. This finding is relevant to the increased interest in the potential use of therapeutic agents that act on CRH receptors in the treatment of irritable bowel syndrome.
S, Fukudo +3 more
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Pharmaceuticals, 2022 Mast cell (MC) plays a central role in intestinal permeability; however, few MC-targeting drugs are currently available for protection of the intestinal barrier in clinical practice.
Yueshan Sun +8 more
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Biomedicines, 2023 Sepsis is associated with dysregulated cortisol secretion, leading to abnormal levels of cortisol in the blood. In the early stages of the condition, cortisol levels are typically elevated due to increased secretion from the adrenal glands.
Ioannis Ilias +6 more
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Corticotropin-releasing hormone receptor-1 in human endometrial cancer
Oncology Reports, 2006 We have previously shown that corticotrophin-releasing hormone (CRH) inhibits the proliferation of Ishikawa (IK) human endometrial carcinoma cell line through the activation of CRH-R1 receptors. Here, we have further investigated the role of CRH and its type-1 receptor in the control of IK cell function, and we carried out a pilot study in tumor ...
GRAZIANI, GRAZIA +8 more
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Brain corticotropin releasing hormone and stress reactivity
Интегративная физиология, 2021 The hypothalamic-pituitary-adrenocortical axis is one of the main components of stress adaptation. Corticotropin-releasing hormone (CRH) coming from the nucleus paraventricularis hypothalami (PVN) is the canonical central regulator of the axis.
Krisztina Bánrévi +6 more
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Regulation of gonadotropins by corticotropin-releasing factor and urocortin
Frontiers in Endocrinology, 2013 While stress activates the hypothalamic-pituitary-adrenal (HPA) axis, it suppresses the hypothalamic-pituitary-gonadal (HPG) axis. Corticotropin-releasing factor (CRF) is a major regulatory peptide in the HPA axis during stress.
Kazunori eKageyama
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