Results 251 to 260 of about 646,725 (280)

Pharmacological Blockade of LPAR1 Does Not Provide Neuroprotection in a Rat Model of Ocular Hypertensive Glaucoma. [PDF]

open access: yesTransl Vis Sci Technol
Kocherlakota S   +6 more
europepmc   +1 more source

Non-Genetically Modified Adoptive Cell Therapies for Solid Tumors: Current Landscape and Future Challenges. [PDF]

open access: yesCancer Immunol Immunother
Luo Q   +10 more
europepmc   +1 more source

Multimeric cytokine receptors

Trends in Endocrinology & Metabolism, 1994
Cytokines are pleiotropic regulators that control proliferation, differentiation, and other cellular functions. They play a pivotal role in the immune and hematopoietic systems, and subsets of cytokines often exhibit similar biologic activities in common target cells. Recent cloning of genes for the cytokine receptors has provided new insights into the
T, Kitamura, T, Ogorochi, A, Miyajima
openaire   +2 more sources

Human cytokine receptors

Journal of Clinical Immunology, 1990
Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.”
S K, Dower, C A, Smith, L S, Park
openaire   +2 more sources

Cytokine receptors

Current Opinion in Immunology, 1991
The molecular characterization of cytokine receptors has progressed rapidly over the past 5 years as a result of availability of radiolabeled cytokines, as well as the identification or creation of cell lines that express significant numbers of receptors at the cell surface.
openaire   +2 more sources

Cytokine-Cytokine Receptor Structure

Science's STKE, 2005
Interleukin-2 (IL-2) is central to the immune response. It forms a complex with three cell surface receptors, IL-2Rα, IL-2Rβ, and IL-2Rγ, to form a complex that signals through activation of downstream tyrosine kinases, JAK3 and STAT. Rickert et al.
openaire   +2 more sources

Cytokine receptor signalling

Nature, 1995
Many cell functions are regulated by members of the cytokine receptor superfamily. Signalling by these receptors depends upon their association with Janus kinases (JAKs), which couple ligand binding to tyrosine phosphorylation of signalling proteins recruited to the receptor complex.
openaire   +2 more sources

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