The role of CAFs in therapeutic resistance in triple negative breast cancer: an emerging challenge. [PDF]
Front Mol BiosciBrogna MR +3 more
europepmc +1 more source
Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao +6 more
wiley +1 more source
Ca<sup>2+</sup> Signaling in Cardiac Fibroblasts: An Emerging Signaling Pathway Driving Fibrotic Remodeling in Cardiac Disorders. [PDF]
BiomedicinesMoccia F, Totaro A, Guerra G, Testa G.
europepmc +1 more source
4D Bioprinted Self‐Folding Scaffolds Enhance Cartilage Formation in the Engineering of Trachea
Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.A bilayer self‐folding scaffold, triggerable by humidity, is fabricated via 4D bioprinting for trachea engineering. An analytical model is derived to predict its radius of curvature, enabling its scalability. Cartilage progenitor cells seeded on the scaffold perceive scaffold final curvature and react to it, by enhancing the upregulation of pro ...
Irene Chiesa +4 more
wiley +1 more source
Targeting Hepatic Stellate Cells for the Prevention and Treatment of Liver Cirrhosis and Hepatocellular Carcinoma: Strategies and Clinical Translation. [PDF]
Pharmaceuticals (Basel)Xiong H, Guo J.
europepmc +1 more source
An Injection‐Molded Modified Silicone Rubber for Cancer‐on‐Chip Applications
Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.This study describes the characterization and application of an injection‐molded functionalized PDMS fluidic insert for the commercially available Micronit system. Modified PDMS can accommodate cell culture and is able to covalently bind proteins for long‐lasting coatings under flow‐conditions.
Ben J. Haspels +7 more
wiley +1 more source
Development and characterization of a novel immortalized human vaginal fibroblast cell line for advanced applications in reproductive health. [PDF]
Reprod Biol EndocrinolCheng LC, You S, Ren T, Qiu J, Hua K.
europepmc +1 more source
Advanced Materials Technologies, EarlyView.Electrospinning enables the hierarchical assembly of nanofiber‐based scaffolds for tissue engineering. However, encapsulated proteins often undergo structural changes. This study used mesoporous silica nanoparticles (MSNs) as protective carriers, mitigating protein denaturation and supporting controlled release.
Vera Citro +5 more
wiley +1 more source
The Landscape of Vascular Endothelial Growth Factor Inhibition in Retinal Diseases. [PDF]
Invest Ophthalmol Vis SciLin JB, Apte RS.
europepmc +1 more source
Advanced Materials Technologies, EarlyView.A hydrophilic, stretchable, nonwoven electrospun fiber mat targeted to be applied in long‐term bioelectronic devices. By incorporating amphiphilic polyethylene glycol block copolymers in a polydimethylsiloxane matrix, the material develops stable hydrophilicity, enhanced breathability, as well as enhanced adhesion to cells.
Joab S. Dorsainvil +7 more
wiley +1 more source