Results 11 to 20 of about 256,322 (306)
Recent developments in receptor tyrosine kinases targeted anticancer therapy [PDF]
Veterinary World, 2016 Novel concepts and understanding of receptors lead to discoveries and optimization of many small molecules and antibodies as anti-cancerous drugs. Receptor tyrosine kinases (RTKs) are such a promising class of receptors under the investigation in past ...
Samir H. Raval +4 more
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Fibroblast Growth Factor Receptor Functions in Glioblastoma [PDF]
Cells, 2019 Glioblastoma is the most lethal brain cancer in adults, with no known cure. This cancer is characterized by a pronounced genetic heterogeneity, but aberrant activation of receptor tyrosine kinase signaling is among the most frequent molecular alterations in glioblastoma.
Ana Jimenez-Pascual +1 more
openaire +4 more sources
Cells, 2023 Cancer is the leading cause of death worldwide; thus, it is necessary to find successful strategies. Several growth factors, such as vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF, FGF2), and transforming growth factor ...
Alessio Ardizzone +10 more
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Progress in Research on the Role of FGF in the Formation and Treatment of Corneal Neovascularization
Frontiers in Pharmacology, 2020 Corneal neovascularization (CNV) is a sight-threatening disease usually associated with inflammatory, infectious, degenerative, and traumatic disorders of the ocular surface.
Mengji Chen +4 more
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Role of Fibroblast Growth Factor Receptor 2 in Pancreatic Cancer: Potential Target for New Therapeutic Approach? [PDF]
, 2015 Fibroblast growth factors and their receptors play a key role in cell proliferation, migration and differentiation. Fibroblast growth factor receptor 2 (FGFR2) is involved in carcinogenesis and its altered expression has been shown in several tumors ...
Angeloni, Antonio +2 more
core +1 more source
Research progress of fibroblast growth factor homologous factor 1 in the pathogenesis of arrhythmia [PDF]
Jichu yixue yu linchuang, 2020 Fibroblast growth factor homologous factor 1 (FHF1) is an intracellular signaling protein, a non-specific fibroblast growth factor that does not bind to fibroblast growth factor receptors. FHF1 combines with the C-terminus of cardiac voltage-gated sodium
QIN Tao, LI Qing, LI Ju-xiang
doaj
Di-san junyi daxue xuebao, 2019 Objective To investigate the changes in the expression of fibroblast growth factor receptors 1-3 (FGFR1-3) at different stages of osteogenic differentiation and clarify the role of FGFR signaling in osteogenic differentiation.
MO Qifei, YANG Peng, SU Nan, CHEN Lin
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The Role of Fibroblast Growth Factor Receptors Inhibitors in Bladder Cancer [PDF]
Journal of Urologic OncologyDysregulation of fibroblast growth factor (FGF)-receptor (FGFR) signaling, which is implicated in various oncogenic processes, including tumor proliferation, survival, migration, invasion, and angiogenesis, has been identified as a critical factor in ...
Ho Kyung Seo +3 more
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A human lung tumor microenvironment interactome identifies clinically relevant cell-type cross-talk. [PDF]
, 2020 BackgroundTumors comprise a complex microenvironment of interacting malignant and stromal cell types. Much of our understanding of the tumor microenvironment comes from in vitro studies isolating the interactions between malignant cells and a single ...
Azizi, Armon +19 more
core +4 more sources
FGFR1 (Fibroblast Growth Factor Receptor 1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on FGFR1 (fibroblast growth factor receptor 1), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire +5 more sources