Results 11 to 20 of about 149,331 (265)
Fibroblast growth factor receptors in breast cancer [PDF]
Tumor Biology, 2017 Fibroblast growth factor receptors are growth factor receptor tyrosine kinases, exerting their roles in embryogenesis, tissue homeostasis, and development of breast cancer.
Shuwei Wang, Zhongyang Ding
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Fibroblast Growth Factor Receptors (FGFRs): Structures and Small Molecule Inhibitors
Cells, 2019 Fibroblast growth factor receptors (FGFRs) are a family of receptor tyrosine kinases expressed on the cell membrane that play crucial roles in both developmental and adult cells.
Shuyan Dai +4 more
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Targeting fibroblast growth factor receptors causes severe craniofacial malformations in zebrafish larvae [PDF]
PeerJ, 2022 Background and Objective A key pathway controlling skeletal development is fibroblast growth factor (FGF) and FGF receptor (FGFR) signaling. Major regulatory functions of FGF signaling are chondrogenesis, endochondral and intramembranous bone development.
Liesbeth Gebuijs +5 more
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Fibroblast Growth Factor Receptors (FGFRs) and Noncanonical Partners in Cancer Signaling
Cells, 2021 Increasing evidence indicates that success of targeted therapies in the treatment of cancer is context-dependent and is influenced by a complex crosstalk between signaling pathways and between cell types in the tumor.
Harriet R. Ferguson +2 more
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Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis [PDF]
Cytokine & Growth Factor Reviews, 2005 Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors. FGFs exert their pro-angiogenic activity by interacting with various endothelial cell surface receptors, including tyrosine kinase receptors, heparan-sulfate proteoglycans, and integrins.
PRESTA, Marco +5 more
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VEGFR1-tyrosine kinase signaling in pulmonary fibrosis
Inflammation and Regeneration, 2021 Vascular endothelial growth factor (VEGF) is not only an important factor for angiogenesis but also lung development and homeostasis. VEGF-A binds three tyrosine kinase (TK) receptors VEGFR1–3.
Hideki Amano +4 more
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Frontiers in Oncology, 2023 Nintedanib is a tyrosine kinase inhibitor of fibroblast growth factor-, vascular endothelial growth factor-, and platelet-derived growth factor receptors.
Shu Yan +6 more
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Recent developments in receptor tyrosine kinases targeted anticancer therapy [PDF]
Veterinary World, 2016 Novel concepts and understanding of receptors lead to discoveries and optimization of many small molecules and antibodies as anti-cancerous drugs. Receptor tyrosine kinases (RTKs) are such a promising class of receptors under the investigation in past ...
Samir H. Raval +4 more
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Journal of Pharmacy and Bioallied Sciences, 2021 Cellular signaling proteins maintain the basic activities of cell and communication, between the cells for normal growth and development and pathological situation as well.
Gururaj Narayana Rao +5 more
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Progress in Research on the Role of FGF in the Formation and Treatment of Corneal Neovascularization
Frontiers in Pharmacology, 2020 Corneal neovascularization (CNV) is a sight-threatening disease usually associated with inflammatory, infectious, degenerative, and traumatic disorders of the ocular surface.
Mengji Chen +4 more
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