Results 31 to 40 of about 149,331 (265)
Heliyon, 2023 Cholangiocarcinomas and urothelial carcinomas are lethal tumors worldwide and only a minority of patients are eligible for surgery at diagnosis.
Demi Wekking +7 more
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Signal transduction by fibroblast growth factor receptors [PDF]
Frontiers in Bioscience, 1999 The fibroblast growth factor family, with its prototype members acidic FGF (FGF-1) and basic FGF (FGF-2), binds to four related receptor tyrosine kinases, expressed on most types of cells in tissue culture. In many respects, the FGF receptors appear similar to other growth factor receptors. Thus, dimerization of receptor monomers upon ligand binding is
P, Klint, L, Claesson-Welsh
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Therapeutic Targeting of Fibroblast Growth Factor Receptors in Gastric Cancer
Gastroenterology Research and Practice, 2015 Chemotherapy has become the global standard treatment for patients with metastatic or unresectable gastric cancer (GC), although outcomes remain unfavorable.
Mikito Inokuchi +5 more
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Di-san junyi daxue xuebao, 2019 Objective To observe the developmental process of murine meniscus after birth and investigate the expression patterns of 3 types of fibroblast growth factor receptors (FGFRs) during this process. Methods Mice at different ages (1 d old and 1, 2, 4, 6 and
LI Fangfang +4 more
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Roles of Fibroblast Growth Factor Receptors in Carcinogenesis [PDF]
Molecular Cancer Research, 2010 Abstract The fibroblast growth factor receptors (FGFR) play essential roles both during development and in the adult. Upon ligand binding, FGFRs induce intracellular signaling networks that tightly regulate key biological processes, such as cell proliferation, survival, migration, and differentiation.
Ellen Margrethe, Haugsten +3 more
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iScience, 2019 Summary: Lung epithelial cells and fibroblasts are key cell populations in lung development. Fibroblasts support type 2 alveolar epithelial cells (AEC2) in the developing and mature lung.
Kazushige Shiraishi +6 more
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Gene expression of growth factor BMP15, GDF9, FGF2 and their receptors in bovine follicular cells
Revista Mvz Cordoba, 2018 Introduction. Growth and follicular maturation involve transformations of various components of the follicle, such as the oocyte, granulosa and techa cells.
Pablo S Reineri +5 more
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Interleukin-17 receptor D (Sef) is a multi-functional regulator of cell signaling
Cell Communication and Signaling, 2021 Interleukin-17 receptor D (IL17RD or IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a single pass transmembrane protein that is reported to regulate several signaling pathways .
Shivangi Pande +2 more
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Receptor Specificity of the Fibroblast Growth Factor Family [PDF]
Journal of Biological Chemistry, 1996 Fibroblast growth factors (FGFs) are essential molecules for mammalian development. The nine known FGF ligands and the four signaling FGF receptors (and their alternatively spliced variants) are expressed in specific spatial and temporal patterns.
D M, Ornitz +7 more
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Basic fibroblast growth factor and its receptors in human embryonic stem cells.
Folia Histochemica et Cytobiologica, 2005 Human embryonic stem cells (hESCs) are pluripotent stem cells with long-lasting capacity to self-renew and differentiate into various cell types of endodermal, ectodermal or mesodermal origin.
Ales Hampl, Petr Dvorak
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