Results 231 to 240 of about 134,321 (267)

Isoforms of Receptors of Fibroblast Growth Factors

Journal of Cellular Physiology, 2014
The breadth and scope of Fibroblast Growth Factor signaling is immense, with documentation of its role in almost every organism and system studied so far. FGF ligands signal through a family of four distinct tyrosine kinase receptors, the FGF receptors (FGFRs).
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Fibroblast Growth Factor 23 and Its Receptors

Therapeutic Apheresis and Dialysis, 2005
Abstract:  Fibroblast growth factor 23 (FGF23) is a circulating factor that plays critical roles in phosphate and vitamin D metabolism, as evidenced by the fact that FGF23 missense mutations cause autosomal dominant hypophosphatemic rickets (ADHR). Autosomal dominant hypophosphatemic rickets is characterized by hypophosphatemia with inappropriately ...
Xijie Yu, Kenneth E. White
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Cellular signaling by fibroblast growth factor receptors

Cytokine & Growth Factor Reviews, 2005
The 22 members of the fibroblast growth factor (FGF) family of growth factors mediate their cellular responses by binding to and activating the different isoforms encoded by the four receptor tyrosine kinases (RTKs) designated FGFR1, FGFR2, FGFR3 and FGFR4.
Veraragavan P. Eswarakumar, Joseph Schlessinger, Irit Lax   +2 more
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Fibroblast Growth Factors and Their Receptors in Parathyroid Disease

World Journal of Surgery, 1998
AbstractFibroblast growth factors (FGFs) comprise a family of polypeptide growth factors implicated in the control of proliferation of glandular tissues. The aim of this study was to determine whether FGFs are produced in normal and abnormal parathyroid glands and if these tissues have the potential to respond to this growth factor family.
Colby L. Eaton, Barnard J. Harrison, Darren Lambert   +2 more
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Immunohistochemical localization of growth factors fibroblast growth factor-1 and fibroblast growth factor-2 and receptors fibroblast growth factor receptor-2 and fibroblast growth factor receptor-3 in normal oral epithelium, epithelial dysplasias, and squamous cell carcinoma

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2002
Fibroblast growth factors (FGFs) and their receptors (FGFRs) have been identified in a variety of carcinomas, but there are few studies concerning their presence in oral cancers. The objective of this study was to determine whether FGF-1, FGF-2, and high affinity receptors FGFR2 and FGFR3 are present in the pathogenesis of oral epithelial dysplasias ...
Linda Jackson-Boeters, George P. Wysocki, Candice A Wakulich, Tom D. Daley   +3 more
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The Role of Fibroblast Growth Factor Receptors in Cancer

2021
Breast cancer accounts for a quarter of all cancers and ranks as the second most common cancer in the world. In particular, triple negative breast cancer is aggressive and lacks targeted therapeutic options. Hence, new therapeutic targets need to be identified for personalised treatment strategies to improve patient outcomes.
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Fibroblast Growth Factor and Epidermal Growth Factor Receptors in Ligament Healing

Clinical Orthopaedics and Related Research, 1997
Although recent in vivo studies indicate that basic fibroblast growth factor hastens the healing and strength of the medical collateral ligament after injury, in vitro studies with epidermal growth factor and basic fibroblast growth factor have shown increased fibroblast proliferation with the exogenous administration of these growth factors.
Stephen H. Liu, Gerald A. M. Finerman, Joseph M. Lane, Vah Panossian   +3 more
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Fibroblast Growth Factors and Their Receptors in Hematopoiesis and Hematological Tumors

Journal of Hematotherapy & Stem Cell Research, 2002
Fibroblast growth factors (FGFs) belong to a family of pleiotropic heparin-binding growth factors. They exert multiple functions on various cell types of mesodermal and neuroectodermal origin, affecting cell proliferation, motility, survival, and differentiation.
MORONI E., DELL'ERA, Patrizia, RUSNATI, Marco, PRESTA, Marco   +3 more
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Expression of fibroblast growth factor 10 and its receptor, fibroblast growth factor receptor 2B, in the bovine corpus luteum

Molecular Reproduction and Development, 2007
AbstractThere is evidence that several fibroblast growth factors (FGFs) are involved in growth and development of the corpus luteum (CL), but many FGFs have not been investigated in this tissue, including FGF10. The objective of this study was to determine if FGF10 and its receptor (FGFR2B) are expressed in the CL.
Castilho, A. C., Giometti, I. C., Berisha, B., Schams, D., Price, C. A., Amorim, Renée Laufer, Papa, P. C., Buratini, J.   +7 more
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Basic fibroblast growth factor and fibroblast growth factor receptor I are implicated in the growth of human astrocytomas

Journal of Neuro-Oncology, 1994
Malignant astrocytomas are highly invasive, vascular neoplasms that comprise the majority of nervous system tumors in humans. A strong association has previously been made between malignancy in human astrocytic tumors and increased expression of certain fibroblast growth factor (FGF) family members, including basic and acidic FGF.
Fumio Yamaguchi, Mitchel S. Berger, Richard S. Morrison, Hideyuki Saya, Janet M. Bruner, Lawrence A. Donehower, Alan M. Yahanda   +6 more
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