Results 1 to 10 of about 2,748,375 (234)
Evaluation of commercially available glucagon receptor antibodies and glucagon receptor expression [PDF]
Communications Biology, 2021 Glucagon is a major regulator of metabolism and drugs targeting the glucagon receptor (GCGR) are being developed. Insight into tissue and cell-specific expression of the GCGR is important to understand the biology of glucagon and to differentiate between
A. B. Bomholt +15 more
semanticscholar +6 more sources
Translational Psychiatry, 2021 Dopamine (DA) and norepinephrine (NE) are catecholamines primarily studied in the central nervous system that also act in the pancreas as peripheral regulators of metabolism.
Despoina Aslanoglou +15 more
doaj +2 more sources
Cellular and Molecular Life Sciences, 2008 Glucagon is a pancreatic peptide hormone that, as a counterregulatory hormone for insulin, stimulates glucose release by the liver and maintains glucose homeostasis. First described as a glucagon binding entity functionally linked to adenylyl cyclase, the glucagon receptor is a member of the family B receptors within the G protein coupled superfamily ...
F. Authier, B. Desbuquois
semanticscholar +5 more sources
Potential role of glucagon like peptide 1 in taste receptors [PDF]
Frontiers in EndocrinologyThe perception of taste is a complex physiological process that extends far beyond the simple detection of flavor molecules, serving as a critical interface between nutrient sensing, metabolic regulation, and feeding behavior.
Jose Luis Eduardo Doval-Caballero +11 more
doaj +2 more sources
Discovery of PACAP and its receptors in the brain
The Journal of Headache and Pain, 2018 Pituitary adenylate-cyclase-activating polypeptide (PACAP) is a 27- or 38-amino acid neuropeptide, which belongs to the vasoactive intestinal polypeptide (VIP)/glucagon/secretin family. PACAP shows particularly high homology (~ 68%) to VIP.
Takahiro Hirabayashi +2 more
doaj +2 more sources
Design Principles of Pancreatic Islets: Glucose-dependent Coordination of Hormone Pulses [PDF]
, 2015 Pancreatic islets are functional units involved in glucose homeostasis. The multicellular system comprises three main cell types; $\beta$ and $\alpha$ cells reciprocally decrease and increase blood glucose by producing insulin and glucagon pulses, while ...
Hara, Manami +2 more
core +17 more sources
Glucagon and Its Receptors in the Mammalian Heart
International Journal of Molecular Sciences, 2023 Glucagon exerts effects on the mammalian heart. These effects include alterations in the force of contraction, beating rate, and changes in the cardiac conduction system axis.
J. Neumann +3 more
semanticscholar +1 more source
Nature Communications, 2022 Glucose homeostasis, regulated by glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1) and glucagon (GCG) is critical to human health.
F. Zhao +21 more
semanticscholar +1 more source
Frontiers in Endocrinology, 2021 The mammalian proglucagon gene (Gcg) encodes three glucagon like sequences, glucagon, glucagon-like peptide-1 (GLP-1), and glucagon-like peptide-2 that are of similar length and share sequence similarity, with these hormones having cell surface receptors,
David M. Irwin, David M. Irwin
doaj +1 more source
Cardiovascular Diabetology, 2023 Background Glucagon is thought to increase heart rate and contractility by stimulating glucagon receptors and increasing 3′,5′-cyclic adenosine monophosphate (cAMP) production in the myocardium.
Ramón Aranda-Domene +4 more
doaj +1 more source