Results 221 to 230 of about 147,749 (309)

Drugs in focus: Budesonide and its role in paediatric gastrointestinal disorders

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Budesonide is a glucocorticoid with strong topical anti‐inflammatory properties and minimal systemic effects due to extensive first‐pass hepatic metabolism. It is designed for targeted delivery within the gastrointestinal (GI) tract and is available in oral and rectal formulations.
Sohail Aziz, Maria Giovanna Puoti, Amit Assa, Zrinjka Misak, Emmanuel Mas, Osvaldo Borrelli, Jernej Dolinšek, Javier Martin‐de‐Carpi, Isabelle Scheers, Christos Tzivinikos, Matjaž Homan, Caterina Strisciuglio   +11 more
wiley   +1 more source

Case Report of a Patient With Psoriasis Vulgaris, Psoriatic Arthritis and Alopecia Universalis Successfully Treated With Tofacitinib and Methotrexate

JEADV Clinical Practice, EarlyView.
Capsule Summary We present a case of a 31‐year‐old female with alopecia universalis, psoriasis vulgaris, and psoriatic arthritis, who showed poor response to prior treatments. Following the initiation of a combination therapy with tofacitinib and methotrexate, significant improvements in joint pain and hair regrowth were observed. This case underscores
Jan Nicolai Wagner, Matthias Augustin, Caroline Gewiss, Carolin Grote, Nesrine Ben‐Anaya   +4 more
wiley   +1 more source

Relapse of Cyclic Cushing Syndrome With a 19-Year Remission: Potential Involvement of COVID-19 in the Relapse. [PDF]

JCEM Case Rep
Takayama K, Mukai K, Motoda S, Ose N, Obata Y, Shimomura I.   +5 more
europepmc   +1 more source

Regulatory Effect and Mechanism of Tanshinone I on Cell Apoptosis in Steroid‐Induced Osteonecrosis of the Femoral Head

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Steroid‐induced osteonecrosis of the femoral head (SIONFH) is a debilitating orthopedic condition. This study investigated the mechanism of Tanshinone I (TsI) in SIONFH modulating apoptosis in SIONFH via the PI3K/AKT/mTOR pathway. A SIONFH rat model was treated with TsI and a PI3K activator. Bone mineral density (BMD), bone volume/total volume
Qing Su, Jia Chen
wiley   +1 more source

Sciatic Nerve Stimulation Mitigates Depression‐Like Behaviors and Memory Deficits in Stressed Mice

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress causes depression and cognitive decline. With limitations in pharmacotherapy, sciatic nerve stimulation (SNS) offers a promising nondrug alternative. This study aimed to explore the therapeutic efficacy of SNS in mitigating stress‐induced depressive behaviors and memory deficits by focusing on astrocytic dysfunction and cellular ...
Chih‐Hao Tien, Pei‐Wen Chen, Ya‐Hsin Hsiao, Chia‐En Wong, Ming‐Tse Wu, Ying‐Fei Chen, Kuo‐Chang Huang, Po‐Hsuan Lee, Kun‐Chia Chang, Heng‐Juei Hsu, Jung‐Shun Lee   +10 more
wiley   +1 more source

Signaling networks governing skeletal muscle growth, atrophy, and cachexia : By. [PDF]

Skelet Muscle
Joshi AS, Tomaz da Silva M, Kumar S, Kumar A.   +3 more
europepmc   +1 more source

Improving responsiveness of health systems to non-communicable diseases.

, 2013
Atun, Rifat, Banatvala, Nicholas, Barreto, Mauricio L, Jaffar, Shabbar, Knaul, Felicia M, Nishtar, Sania, Nyirenda, Moffat, Piot, Peter   +7 more
core   +1 more source

Post‐operative joint stiffness after Bereiter trochleoplasty does not affect 2‐year improvement in patient‐reported outcomes. A prospective cohort study of 374 Bereiter trochleoplasties

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Bereiter trochleoplasty (TP) is a well‐described procedure to address trochlear dysplasia (TD). Post‐operative joint stiffness with reduced range of motion (ROM) is a common complication usually requiring arthroscopically assisted manipulation (AAM) with the removal of adhesions and scar tissue. Inferior clinical outcomes after TP have
Christian Dippmann, Christos Soleas, Anke Simone Rechter, Volkert Siersma, Kristoffer Weisskirchner Barfod, Peter Lavard   +5 more
wiley   +1 more source

Immunosuppressive Therapies in Pulmonary Sarcoidosis: A Practical, Evidence-Based Review. [PDF]

J Clin Med
Dhanani Z, Gupta R.
europepmc   +1 more source

Vocal Fold Scar Treatment via Controlled Dexamethasone Delivery With a Light‐Activatable Implant

The Laryngoscope, EarlyView.
A light‐activatable dexamethasone implant was employed for the treatment of vocal fold (VF) scarring in a rabbit model. The implant enables controlled, repeatable drug release via near‐infrared laser irradiation, improving biomechanics, vibratory function, and histological architecture at the injury site.
Denzel Ryan D. Cruz, Nour Awad, Avery Zheng, Alexander Karabachev, Charles Farbos de Luzan, Yoonjee C. Park, Gregory R. Dion   +6 more
wiley   +1 more source