Results 131 to 140 of about 301,762 (292)

An Allele of Glutamate Formiminotransferase Triggers 5‐Methyl‐Tetrahydrofolate‐to‐MeFox Conversion and Facilitates Folate Biofortification in Maize

Advanced Science, EarlyView.
This work demonstrates the distinct roles of the glutamate formiminotransferase (GFT) enzyme in plants. The GFT triggers the conversion of 5‐methyl‐tetrahydrofolate to MeFox in plants, a process distinct from its role as a formiminotransferase in mammals.
Tong Lian, Wenzhu Guo, Yanjing Wang, Weiwei Wen, Weixuan Wang, Ling Jiang, Qiuju Liang, Ji'an Liu, Haijun Liu, Yuan Xue, Lixu Pan, Qiaoquan Liu, Ping Yin, Delin Zhang, Jianbing Yan, Chunyi Zhang   +15 more
wiley   +1 more source

Conductive Nanocomposite Hydrogels for Neural Tissue Engineering: A Systematic Scoping Review of Recent Trends

Advanced Science, EarlyView.
This systematic scoping review explores conductive nanocomposite hydrogels for neural tissue engineering(NTE), focusing on composition, cellular interactions, and neural differentiation capabilities. The review synthesizes data from 125 studies, examining important features including commonly used materials, cell types, and differentiation strategies ...
Mohammad Moghaddasi, Busra Oktay, Ayse Betul Bingol, Reyhan Yanikoglu, Meryem Muslu, Ibrahim T Ozbolat, Cem Bulent Ustundag   +6 more
wiley   +1 more source

Vesicular glutamatergic transmission in noise-induced loss and repair of cochlear ribbon synapses [PDF]

, 2019
Noise-induced excitotoxicity is thought to depend on glutamate. However, the excitotoxic mechanisms are unknown, and the necessity of glutamate for synapse loss or regeneration is unclear. Despite absence of glutamatergic transmission from cochlear inner
Carlquist, Jason, Davis, Bethany, Fitzpatrick, James A.J., Gantz, Jay A, Hirose, Keiko, Kallogjeri, Dorina, Kim, Kyunghee X, Li, Song-Zhe, Ohlemiller, Kevin K, Payne, Shelby, Rutherford, Mark A, V-Ghaffari, Babak, Yang-Hood, Aizhen   +12 more
core   +1 more source

Parasubthalamic Glutamatergic Neurons Coordinate Cardiovascular Homeostasis and Locomotion in Mice

Advanced Science, EarlyView.
PSTNVglut2 neurons function as a new central baroreflex hub via projections to the NTS, modulating parasympathetic cardiac output to maintain cardiovascular homeostasis while synchronously regulating locomotion. Blood pressure fluctuations negatively correlate with locomotor performance.
Ming‐Xuan Lu, Jin‐Yin Huang, Xing‐Zhe Xu, Ji‐Yu Sun, Dan‐Ni Zou, Jia‐Yao Zhang, Chen Chi, Qi Zhang, Wei‐Cai Liu   +8 more
wiley   +1 more source

Calcitonin Gene‐Related Peptide (CGRP)‐Expressing Neurons in the External Lateral Parabrachial Area Regulate Pain‐Induced Sleep Disturbances

Advanced Science, EarlyView.
Lynch et al., identified novel targets on the wake‐promoting pathways that can effectively treat pain‐induced sleep disturbances. The authors demonstrated that Calcitonin gene‐related peptide‐expressing neurons (CGRP) in the external lateral parabrachial nucleus (PBelCGRP) serve as the primary relay node for pain stimuli that cause sleep disruption ...
Nicole Lynch, Roberto De Luca, Richard L Spinieli, Enrico Rillosi, Renner C Thomas, Samuel Sailesh, Nishta Gangeddula, Janayna D Lima, Sathyajit S Bandaru, Elda Arrigoni, Agustin Melo‐Carrillo, Rami Burstein, Stephen Thankachan, Satvinder Kaur   +13 more
wiley   +1 more source

Two Signaling Modes Are Better than One: Flux-Independent Signaling by Ionotropic Glutamate Receptors Is Coming of Age

Biomedicines
Glutamate is the major excitatory neurotransmitter in the central nervous system. Glutamatergic transmission can be mediated by ionotropic glutamate receptors (iGluRs), which mediate rapid synaptic depolarization that can be associated with Ca2+ entry ...
Valentina Brunetti, Teresa Soda, Roberto Berra-Romani, Giovambattista De Sarro, Germano Guerra, Giorgia Scarpellino, Francesco Moccia   +6 more
doaj   +1 more source

Integrative Omics Reveals Glutamine Catabolism‐Driven Apoptotic Suppression in Monocytes upon Mechanical Unloading

Advanced Science, EarlyView.
This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding, Fan Tong, Mingqiu Liu, Pin Yang, Jing Zeng, Yinghua Wei, Chunlin Li, Dong Li, Cheng Chang, Yangjun Zhang, Shaoqiong Yi, Fan Hu, Wenjie Shu, Lingqiang Zhang, Chun‐Ping Cui   +14 more
wiley   +1 more source

Blunted Cystine–Glutamate Antiporter Function in the Nucleus Accumbens Promotes Cocaine-induced Drug Seeking [PDF]

, 2008
Repeated cocaine alters glutamate neurotransmission, in part, by reducing cystine–glutamate exchange via system xc−, which maintains glutamate levels and receptor stimulation in the extrasynaptic compartment.
Abdulhameed, Omer, Baker, David A., Grier, Mark D., Kau, Kristen S., Madayag, Aric, Mantsch, John R.   +5 more
core   +1 more source

Glutamate receptors and schizophrenia [PDF]

Journal of Psychopharmacology, 1987
B.S. Meldrum, R.W. Kerwin
openaire   +3 more sources

Auxin‐Producing Pseudomonas Recruited by Root Flavonoids Increases Rice Rhizosheath Formation through the Bacterial Histidine Kinase Under Soil Drying

Advanced Science, EarlyView.
Drought is a major cause of crop losses across agricultural regions. Rhizosheath formation enhances plant resistance to drought. Polyploids may tolerate stress more effectively through increased interactions with bacteria. However, the contributions of tetraploid rice associated microbiota to rhizosheath formation under soil drying remain unclear ...
Feiyun Xu, Yongsen Wang, Jinyong Yang, Xue Zhang, Ke Wang, Fan Ding, Jiayin Pang, Lu Tong, Chuqi Bai, Shu Chen, Leyun Sun, Chongxuan Du, Ju Fang, Mengqiang Xu, Liang Li, Xin Yu, Jiahong Gengli, Jianping Liu, Qian Zhang, Zhengrui Wang, Yiyong Zhu, Huanyuan Zhang‐Zheng, Jianhua Zhang, Weifeng Xu   +23 more
wiley   +1 more source