Results 51 to 60 of about 2,659,590 (353)
Metabotropic glutamate receptors: physiology, pharmacology, and disease.
Annual Review of Pharmacology and Toxicology, 2010 The metabotropic glutamate receptors (mGluRs) are family C G-protein-coupled receptors that participate in the modulation of synaptic transmission and neuronal excitability throughout the central nervous system.
C. Niswender, P. Conn
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Binding of glutamate to the umami receptor [PDF]
Biophysical Chemistry, 2010 The umami taste receptor is a heterodimer composed of two members of the T1R taste receptor family: T1R1 and T1R3. It detects glutamate in humans, and is a more general amino acid detector in other species. We have constructed homology models of the ligand binding domains of the human umami receptor (based on crystallographic structures of the ...
Lopez Cacales, J. +3 more
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Biomédica: revista del Instituto Nacional de Salud, 2017 La encefalitis asociada a anticuerpos contra receptores N-metil-D-aspartato es un síndrome neurológico que se presenta más comúnmente en mujeres jóvenes y frecuentemente se asocia al teratoma de ovario.
José Bustos +5 more
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Studies of NMDA receptor function and stoichiometry with truncated and tandem subunits [PDF]
, 2003 The subunits that compose eukaryotic glutamate ion channel receptors have three transmembrane domains (TMs) and terminate with intracellular tails that are important for controlling channel expression and localization.
Colquhoun, D., Schorge, S.
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Glutamate receptors in the kidney [PDF]
Nephrology Dialysis Transplantation, 2015 l-Glutamate (l-Glu) plays an essential role in the central nervous system (CNS) as an excitatory neurotransmitter, and exerts its effects by acting on a large number of ionotropic and metabotropic receptors. These receptors are also expressed in several peripheral tissues, including the kidney.
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Astroglial Glutamate Signaling and Uptake in the Hippocampus
Frontiers in Molecular Neuroscience, 2018 Astrocytes have long been regarded as essentially unexcitable cells that do not contribute to active signaling and information processing in the brain. Contrary to this classical view, it is now firmly established that astrocytes can specifically respond
Christine R. Rose +7 more
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A Review of Molecular Imaging of Glutamate Receptors
Molecules, 2020 Molecular imaging with positron emission tomography (PET) and single photon emission computed tomography (SPECT) is a well-established and important in vivo technique to evaluate fundamental biological processes and unravel the role of neurotransmitter ...
Jong-Hoon Kim +3 more
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Metabotropic Glutamate Receptors
Journal of Biological Chemistry, 2015 Background: C. elegans encodes three metabotropic glutamate receptors: mgl-1, mgl-2, and mgl-3. Results: mgl-1 and mgl-3, but not mgl-2, modulate activity in the neural circuit underlying feeding behavior.
J. Dillon +8 more
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An unexpected role for a glutamate receptor
Science, 2023 γ-Aminobutyric acid acts on a glutamate receptor, evoking synaptic ...
Coombs, Ian D, Farrant, Mark
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The DLGAP family: neuronal expression, function and role in brain disorders
Molecular Brain, 2017 The neurotransmitter glutamate facilitates neuronal signalling at excitatory synapses. Glutamate is released from the presynaptic membrane into the synaptic cleft.
Andreas H. Rasmussen +2 more
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