Results 81 to 90 of about 51,381 (211)

Proto-oncogene c-jun expression is induced by AML1-ETO in a JNK dependent manner:possible role in the pathogenesis of acute myeloid leukemia [PDF]

, 2003
Overexpression of proto-oncogene c-jun and constitutive activation of the Jun NH2-terminal kinase (JNK) signaling pathway have been implicated in the leukemic transformation process.
Elsaesser, Annika
core  

Cell surface lectins of human granulocytes: their expression is modulated by mononuclear cells and granulocyte/macrophage colony-stimulating factor

, 1990
International audienceThis paper presents the characterization of a sugar-specific receptor on the surface of human circulating poly-morphonuclear cells.
Kieda, Claudine, Monsigny, Michel, Grillon, Catherine   +2 more
core   +1 more source

Ligand binding domain of granulocyte colony-stimulating factor receptor.

Journal of Biological Chemistry, 1994
The amino-terminal domain of the cytokine receptor homologous region (BN domain; roughly 100 amino acid residues) in the receptor for murine granulocyte colony-stimulating factor (G-CSF) was secreted as a maltose-binding protein fusion into the Escherichia coli periplasm.
O, Hiraoka, H, Anaguchi, K, Yamasaki, R, Fukunaga, S, Nagata, Y, Ota   +5 more
openaire   +2 more sources

Molecular bases of the modulation of coagulation factor levels

, 2009
The maintenance of blood uidity within the vascular system is ensured by the balance between procoagulant and anticoagulant components. Hemostasis and blood coagulation are processes regulated by a complex network of interactions, involving plasma ...
Caruso, Pierpaolo
core  

Characterization of the human granulocyte-macrophage colony-stimulating factor receptor.

Journal of Biological Chemistry, 1988
Human granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine derived from activated T cells, endothelial cells, fibroblasts, and macrophages. It stimulates myeloid and erythroid progenitors to form colonies in semisolid medium in vitro, as well as enhancing multiple differentiated functions of mature neutrophils, macrophages, and ...
J, DiPersio, P, Billing, S, Kaufman, P, Eghtesady, R E, Williams, J C, Gasson   +5 more
openaire   +2 more sources

A Novel Functional Epitope Formed by Domains 1 and 4 of the Human Common beta -Subunit Is Involved in Receptor Activation by Granulocyte Macrophage Colony-stimulating Factor and Interleukin 5*

, 2015
The receptors for human interleukins 3 and 5 and granulocyte macrophage colony-stimulating factor are composed of ligand-specific α-subunits and a common β-subunit (βc), the major signaling entity.
Ford, Sally, Young, Ian, Murphy, James, Wiedemann, Ursula, Ollis, David, Carr, Paul D   +5 more
core   +1 more source

Apoptosis is essential for neutrophil functional shutdown and determines tissue damage in experimental pneumococcal meningitis. [PDF]

, 2009
During acute bacterial infections such as meningitis, neutrophils enter the tissue where they combat the infection before they undergo apoptosis and are taken up by macrophages.
Häcker Georg, Bianca Obermaier, Georg Häcker, Robert Paul, Hans Häcker, Obermaier, Bianca, Paul Robert, Frankenberg, Tobias, Koedel, Uwe, Uwe Koedel, Frankenberg Tobias, Paul, Robert, Susanne Kirschnek, Kirschnek, Susanne, Tobias Frankenberg, Kirschnek Susanne, Obermaier Bianca, Koedel Uwe, Häcker, Hans, Häcker, Georg, Häcker Hans   +20 more
core   +1 more source

Effects of granulocyte colony-stimulating factor on night sleep in humans

, 1999
Numerous animal studies suggest that cytokines such as interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) mediate increased sleep amount and intensity observed during infection and are, moreover, involved in physiological sleep regulation.
T. Fenzel, D. Hermann, T. Pollmächer, D. Hinze-Selch, A. Schuld, J. Mullington, F. Holsboer   +6 more
core   +1 more source

Identification of a 14-3-3 binding sequence in the common beta chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors that is serine-phosphorylated by GM-CSF

, 1999
Identification of a 14-3-3 binding sequence in the common beta chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors that is serine-phosphorylated by GM ...
FC Stomski (15805250), DT Thomas (15805373), CJ Bagley (15805370), RK Andrews (11139912), M Dottore (13526098), W Winnall (13526164), MC Berndt (15805376), AF Lopez (15805238), J Woodcock (12224105), Mark Guthridge (13072134)   +9 more
core  

The human granulocyte/macrophage colony-stimulating factor receptor alpha 2 isoform influences haemopoietic lineage commitment and divergence.

, 2003
A number of alternatively spliced isoforms of haemopoietic growth factor receptors (HGFRs) have been described, but their role in human haemopoiesis remains undetermined.
Slater NJ, Heyworth, Clare M., Rajesh Chopra, Heyworth CM, Chopra, Rajesh, Chopra R, Clare M. Heyworth, Rothwell, Dominic G., Baker, Patrick, Masafumi Yamaguchi, Dominic G. Rothwell, Yamaguchi, Masafumi, Nicholas J. Slater, Patrick Baker, Rothwell DG, Baker P, Yamaguchi M, Slater, Nicholas J.   +17 more
core   +1 more source