Results 61 to 70 of about 51,381 (211)

Effect of intrauterine granulocyte-colony stimulating factor administration on in vitro fertilization outcome in women with moderate-to-severe endometriosis: An RCT

International Journal of Reproductive BioMedicine, 2021
Background: Nearly 25-50% of infertile women have endometriosis. There are reports of disorders in the expression of granulocyte colony-stimulating factor (G-CSF) receptors in women with endometriosis.
Ladan Kashani, Ashraf Moini, Tayebeh Esfidani, Nazila Yamini, Shima Mohiti   +4 more
doaj   +1 more source

Prognostic Relevance of Cytokine Receptor Expression in Acute Myeloid Leukemia: Interleukin-2 Receptor α-Chain (CD25) Expression Predicts a Poor Prognosis. [PDF]

PLoS ONE, 2015
A variety of cytokine/cytokine receptor systems affect the biological behavior of acute leukemia cells. However, little is known about the clinical relevance of cytokine receptor expression in acute myeloid leukemia (AML).
Kazunori Nakase, Kenkichi Kita, Taiichi Kyo, Takanori Ueda, Isao Tanaka, Naoyuki Katayama   +5 more
doaj   +1 more source

Enteral granulocyte colony-stimulating factor for the treatment of mild (stage I) necrotizing enterocolitis: a placebo-controlled pilot study

, 2006
Background/Purpose: The presence of granulocyte colony-stimulating factor (G-CSF) in human milk and the expression of G-CSF receptors on intestinal villous enterocytes of neonates suggest that G-CSF has a role in the development and integrity of the ...
Tekinalp, Gulsevin, Canpolat, Fuat Emre, Yigit, ŞULE, Yurdakok, MURAT, Korkmaz, Ayse   +4 more
core   +1 more source

A strategy to design protein-based antagonists against type I cytokine receptors.

PLoS Biology
Excessive cytokine signaling resulting from dysregulation of a cytokine or its receptor can be a main driver of cancer, autoimmune, or hematopoietic disorders.
Timo Ullrich, Olga Klimenkova, Christoph Pollmann, Asma Lasram, Valeriia Hatskovska, Kateryna Maksymenko, Matej Milijaš-Jotić, Lukas Schenk, Claudia Lengerke, Marcus D Hartmann, Jacob Piehler, Julia Skokowa, Mohammad ElGamacy   +12 more
doaj   +1 more source

Dopaminergic Stimulation of Myeloid Antigen-Presenting Cells Attenuates Signal Transducer and Activator of Transcription 3-Activation Favouring the Development of Experimental Autoimmune Encephalomyelitis

Frontiers in Immunology, 2018
The dual potential to promote tolerance or inflammation to self-antigens makes dendritic cells (DCs) fundamental players in autoimmunity. Previous results have shown that stimulation of dopamine receptor D5 (DRD5) in DCs potentiates their inflammatory ...
Carolina Prado, Michela Gaiazzi, Hugo González, Valentina Ugalde, Alicia Figueroa, Francisco J. Osorio-Barrios, Ernesto López, Alvaro Lladser, Emanuela Rasini, Franca Marino, Mauro Zaffaroni, Marco Cosentino, Rodrigo Pacheco, Rodrigo Pacheco   +13 more
doaj   +1 more source

Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients

, 2011
Introduction: Systemic inflammation (e.g. following surgery) involves Toll-like receptor (TLR) signaling and leads to an endocrine stress response. This study aims to investigate a possible influence of TLR2 and TLR4 single nucleotide polymorphisms (SNPs)
Carsten Schwenke, Matthias Schott, Koch, Alexander, Stefan R Bornstein, Ralf R Schumann, Schott, Matthias, Lutz Hamann, Hamann, Lutz, Bornstein, Stefan R., Schwenke, Carsten, Alexander Koch, Muhammed Kurt, Zacharowski, Kai, Kai Zacharowski, Olaf Boehm, Schumann, Ralf R., Grotemeyer, Dirk, Kurt, Muhammed, Boehm, Olaf, Dirk Grotemeyer   +19 more
core   +1 more source

Subclassification of patients with acute myelogenous leukemia based on chemokine responsiveness and constitutive chemokine release by their leukemic cells

Haematologica, 2007
Background and Objectives Chemokines are soluble mediators involved in angiogenesis, cellular growth control and immunomodulation. In the present study we investigated the effects of various chemokines on proliferation of acute myelogenous leukemia (AML)
Øystein Bruserud, Anita Ryningen, Astrid Marta Olsnes, Laila Stordrange, Anne Margrete Øyan, Karl Henning Kalland, Bjørn Tore Gjertsen   +6 more
doaj   +1 more source

Neutrophils activated by granulocyte-macrophage colony-stimulating factor express receptors for interleukin-3 which mediate class II expression

, 1995
Freshly isolated peripheral blood neutrophils, unlike monocytes and eosinophils, do not bind interleukin-3 (IL-3) or respond to IL-3). We show that neutrophils cultured for 24 hours in granulocyte-macrophage colony-stimulating factor (GM-CSF) express ...
Smith, W., van den Hueven, C., Lopez, A., Hawrylowicz, C., Qiuy, S., Guida, L., Vadas, M., Korpelainen, E., Gillis, D.   +8 more
core   +1 more source

Lack of effect of the human GM-CSF analog E21R on the survival of primary human acute myeloid leukemia cells

, 2004
The granulocyte-macrophage colony-stimulating factor (GM-CSF) analog E21R binds to the GM-CSF receptor complex with low affinity and acts as a competitive antagonist.
Jakupovic, I., Khwaja, A., Grandage, V.L., Linch, D.C.   +3 more
core  

Prolonged, granulocyte–macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha-5

, 2011
S in the presence or absence of an anti-CD118 (type I interferon receptor) blocking antibody (filled bars) or irrelevant control. Using either irrelevant control antibodies, specific granulocyte–macrophage colony-stimulating factor (GM-CSF) and/or TNFα ...
Debbie Hardie (94358), Karim Raza (23437), See-Heng Wong (94361), Andrew Filer (23434), Sian Lax (74987), Greg Parsonage (23436), Christopher D Buckley (23441), Leigh D Church (94360), Mike Salmon (8720), Janet M Lord (68018), Magdalena Bik (94357), Emily Trebilcock (94362), Dagmar Scheel-Toellner (68012), Katherine Howlett (94359)   +13 more
core   +1 more source