Results 51 to 60 of about 23,298 (234)
First description of a histamine receptor of class 2 (HRH2) in a protochordate: expression during blastogenesis and role in regulation of ciliary beat frequency [PDF]
, 2016 Histaminergic receptors belong to the family of seven-transmembrane \u3b1-helix domain receptors classified in mammals into four distinct classes. Despite being widely studied in vertebrates, few data are available on the invertebrate receptors, with ...
Cima, Francesca
core
Histamine can be Formed and Degraded in the Human and Mouse Heart [PDF]
, 2023 Histamine is metabolized by several enzymes in vitro and in vivo. The relevance of this metabolism in the mammalian heart in vivo is unclear. However, histamine can exert positive inotropic effects (PIE) and positive chronotropic effects (PCE) in humans ...
Buchwalow, Igor B. +12 more
core +1 more source
Central Effect of Exogenous Histamine on Pain Induced by Sub-Plantar Injection of Formalin in Rabbits [PDF]
Veterinary Research Forum, 2010 In the present study, the effects of intracerebroventricular (ICV) administration of normal saline (control), histamine, mepyramine (a histamine H1-receptor antagonist) and ranitidine (a histamine H2-receptor antagonist) were investigated on the formalin-
Esmaeal Tamaddonfard
doaj
Increased accuracy of ligand sensing by receptor diffusion on cell surface [PDF]
Physical Review E 82, 041902 (2010), 2010 The physical limit with which a cell senses external ligand concentration corresponds to the perfect absorber, where all ligand particles are absorbed and overcounting of same ligand particles does not occur. Here we analyze how the lateral diffusion of receptors on the cell membrane affects the accuracy of sensing ligand concentration.
arxiv +1 more source
Molecular Nutrition &Food Research, EarlyView.In this study we utilized proteomic profiling to investigate mechanisms linked to the cancer‐inhibitory effect of cranberry proanthocyanidins (CPACs) on reflux‐induced esophageal adenocarcinoma in a rat model. The results indicate that CPAC inhibits cancer through targeting multiple hallmarks of cancer known to be dysregulated in progression to ...
Yun Zhang +7 more
wiley +1 more source
T lymphocytes as a target of histamine action [PDF]
, 2012 Histamine is one of the most important biogenic amines in medicine and biology but its role in allergy, autoimmune and neoplastic diseases has not yet been fully defined.
Ciebiada, Maciej +3 more
core +2 more sources
Mast cells are critical for protection against peptic ulcers induced by the NSAID piroxicam. [PDF]
PLoS ONE, 2011 Many commonly used non-steroidal anti-inflammatory drugs (NSAIDs) also cause gastrointestinal toxicity, including the development of life-threatening peptic ulcers. We report that mast cell-deficient mice have an extremely high incidence of severe peptic
Daniel D Hampton, Laura P Hale
doaj +1 more source
Pathogenesis of Melasma Explained
International Journal of Dermatology, EarlyView.Pathophysiology of melasma. ABSTRACT This review provides an in‐depth analysis of the pathophysiology of melasma and highlights recent studies that elucidate its underlying mechanisms. Given the prevalence of melasma, a thorough understanding of its pathogenesis is critical for the development of effective treatment strategies.
Lara Ali, Firas Al Niaimi
wiley +1 more source
The Effects of Histamine H3 Receptors on Contractile Responses on Rat Gastric Fundus [PDF]
, 2006 The aim of this study is to determine the effects of histamine receptors on the gastrointestinal system smooth muscle contractions and the role of histamine H3 receptors on these effects.
Aşkın Hekimoğlu, Ramazan Çiçek
core
Role of the Histaminergic System in the Inhibitory Effect of Melatonin on Broiler Chicken Feed Intake [PDF]
Poultry Science JournalPrior investigations have postulated that melatonin, a prominent hormone produced by the pineal gland, can reduce animal food consumption. This study was designed to evaluate the involvement of central histamine H1 and H2 receptors in regulating ...
Majid Taati +2 more
doaj +1 more source