Results 201 to 210 of about 3,330,792 (348)

Characterization of IgG Fc receptors induced by human cytomegalovirus.

Journal of General Virology, 1989
Xu-Bin, Tsugiya Murayama, K. Ishida, Toru Furukawa   +3 more
semanticscholar   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Diversification of IgG effector functions

International Immunology, 2017
S. Bournazos, J. Ravetch
semanticscholar   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Increased prevalence of autoantibodies neutralizing IFNλ2/3 in young individuals with cystic fibrosis. [PDF]

J Hum Immun
Groen K, Tran C, Kuratli R, Egan ME, Trück J, Bruscia EM, Emmenegger M, Hale BG.   +7 more
europepmc   +1 more source

Activating and inhibitory IgG Fc receptors on human DCs mediate opposing functions.

Journal of Clinical Investigation, 2005
A. Boruchov, G. Heller, M. Verì, E. Bonvini, J. Ravetch, James W. Young   +5 more
semanticscholar   +1 more source

Coacervates Made of Elastin‐Like Polypeptides Fused with Melanocyte‐Stimulating Hormone and Monocyte Chemoattractant Protein Enhance Skin Wound Healing in Spinal Cord‐Injured Mice

Advanced Healthcare Materials, EarlyView.
Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar, Dhruv Patel, Greeshma Manjunath, Shashank Madhavan, Ashley Mathew, Dnyaneshwari Rananavare, Jahnavi Shah, Francois Berthiaume   +7 more
wiley   +1 more source

Development of tCAP(N3): Affinity Peptide-Aided, pH-Triggered Strategy for Site-Specific Native IgG Modification. [PDF]

Chemistry
Kawakami H, Rafique A, Tsuda S, Nagashima A, Nohara Y, Dozono N, Sakamoto K, Masuda S, Kiyoshi M, Shibata H, Ishii-Watabe A, Yoshiya T, Ito Y.   +12 more
europepmc   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

A longitudinal study of children identifies antibody Fc-mediated functions and antigen targets of immunity to Plasmodium vivax malaria. [PDF]

Immunity
Opi DH, Longley RJ, Takashima E, Spelman T, Tayipto Y, Schoffer K, Brewster J, Reiling L, Wines BD, Kiniboro B, Siba P, Harbers M, Hogarth M, Tsuboi T, Robinson LJ, Mueller I, Beeson JG.   +16 more
europepmc   +1 more source