Results 271 to 280 of about 3,330,792 (348)

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

A targeting lentiviral vector for generation of CAR-T cells in vivo. [PDF]

Sci Rep
Tuerxunyiming M, Yin JM, Zhu P, Liu M, Fu Z, Zhao Q.   +5 more
europepmc   +1 more source

Immobilized IgG-containing immune complexes require platelets to recruit neutrophils during inflammation. [PDF]

J Clin Invest
Bellio M, Allaeys I, Doré E, Vaillancourt M, Lévesque T, Monteil M, Vallières N, Desaulniers P, Bertrand N, Washington VA, Senis Y, Lacroix S, Fortin P, Belleannée C, Boilard E.   +14 more
europepmc   +1 more source

The making of multispecific immunoglobulins - a clinical perspective. [PDF]

MAbs
Brinkmann U, Kontermann RE.
europepmc   +1 more source

Different antibody isotypes against tuberculosis: what we know and what we need to know. [PDF]

Front Immunol
Li H, Li H.
europepmc   +1 more source

Asymmetrically glycosylated IgG1 antibodies are universal and drive human disease. [PDF]

Nat Commun
Azzam T, Bournazos S, Gunduz H, Adams T, Flowers MW, Niejadlik EG, Duong V, Brown TJ, Roberts AM, Sastre DE, Avci FY, Lam WA, Cantaert T, Roberts BR, Diamond B, Ravetch JV, Du JJ, Sundberg EJ.   +17 more
europepmc   +1 more source

Integrins α3 and α6 promote Th17 cell migration by activating the purinergic receptor P2X4. [PDF]

Purinergic Signal
Hamoudi C, Lashgari A, Aoudjit F.
europepmc   +1 more source

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IgG Fc Receptors

Annual Review of Immunology, 2001
Since the description of the first mouse knockout for an IgG Fc receptor seven years ago, considerable progress has been made in defining the in vivo functions of these receptors in diverse biological systems. The role of activating FcγRs in providing a critical link between ligands and effector cells in type II and type III inflammation is now well ...
J V, Ravetch, S, Bolland
openaire   +3 more sources