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Interleukin-1 receptor antagonist

2000
Interleukin-1 (IL-1) is a proinflammatory cytokine produced by a wide variety of cell types with an equally pleiotropic range of activities including the induction of fever, hypotension, adhesion molecule expression, neutrophilia, cartilage destruc­tion, prostanoid production, and induction of the expression of a number of other cytokines. Two forms of
openaire   +2 more sources

The interleukin-1/interleukin-1-receptor interaction

Annales de l'Institut Pasteur / Immunologie, 1987
J.W. Lowenthal, H.R. MacDonald
openaire   +2 more sources

The Role of the Interleukin-1–Receptor Antagonist in Blocking Inflammation Mediated by Interleukin-1

New England Journal of Medicine, 2000
Approaches involving the blockade of inflammatory cytokines such as interleukin-1 and tumor necrosis factor α (TNF-α) are entering mainstream clinical medicine: antibodies against TNF-α and soluble...
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Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19

New England Journal of Medicine, 2021
Michelle A Detry   +2 more
exaly  

Interleukin-6: A Novel Target for Cardio-Cerebrovascular Diseases

Frontiers in Pharmacology, 2021
Ai-ping Wang
exaly  

Interleukin-1-Induced Hypotension and the Effect of an Interleukin-1 Receptor Antagonist

1993
The systemic effects of high doses (> 1μg/kg) of intravenously administered interleukin (IL-1) in animals include hypotension, decreased systemic vascular resistance, depressed myocardial function, lactic acidosis, leukopenia, thrombocytopenia, vascular leak, pulmonary congestion, and tissue neutrophilic infiltration with necrosis [1, 2].
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Phase 3 Trial of Interleukin-1 Trap Rilonacept in Recurrent Pericarditis

New England Journal of Medicine, 2021
Allan L Klein   +2 more
exaly  

Asymmetrical Expression of Interleukin-1, Interleukin-1 Receptor and Erythropoietin Receptor in Mouse Brain Hemispheres [PDF]

open access: possibleNeuroembryology and Aging, 2004
V. V. Abramov   +4 more
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