Results 31 to 40 of about 196,653 (259)
Frontiers in GeneticsBackgroundAcute Respiratory Distress Syndrome (ARDS) is a severe lung condition posing significant health risks. Observational studies have indicated a potential linkage between ARDS and various interleukins, such as Interleukin-8, −2, −6, and −1β ...
Jia-wei Ma +3 more
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Gastroenterologìa, 2015 Aryl hydrocarbon receptor (AhR) — transcription factor activated by a large number of environmental agents, and may play a role in the pathogenesis of inflammatory bowel diseases in humans and mouse models.
O.S. Zherebiatiev, O.M. Kamyshnyi
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Interleukin‐1 receptor accessory protein interacts with the type II interleukin‐1 receptor
FEBS Letters, 1998 Stably transfected HEK‐293 cells express on their surface the murine type II IL‐1 receptor (mIL‐1RII) as demonstrated by FACS analysis using the mAb 4E2, however binding of [125I]‐hrIL‐1β to these cells is nearly absent. Saturable high affinity binding of [125I]‐hrIL‐1β is observed when the murine IL‐1 receptor accessory protein (mIL‐1RAcP) is ...
Sophie Layé +3 more
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Two‐chain structure of the interleukin 1 receptor [PDF]
FEBS Letters, 1988 By crosslinking radioiodinated recombinant human IL1 α to mouse EL4 thymoma cells we have identified in addition to the known IL1‐binding proteins of 80 kDa, a second IL1‐binding protein of about 40 kDa. This second binding protein could be demonstrated most easily when crosslinking to higher protein complexes was inhibited.
Klaus Resch +4 more
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Cytokines of Birds: Conserved Functions [PDF]
, 2001 Targeted disruptions of the mouse genes for cytokines, cytokine receptors, or components of cytokine signaling cascades convincingly revealed the important roles of these molecules in immunologic processes. Cytokines are used at present as drugs to fight
Göbel, Thomas W. F. +4 more
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The interleukin‐1 receptor antagonist influences interleukin‐1 effects in rat and mouse [PDF]
Mediators of Inflammation, 1992 In this work we have focused on the ability of interleukin‐1 to induce an acute phase protein response and a degranulation of polymorphonuclear leukocytes in vivo. The capacity of the interleukin‐1 receptor antagonist to influence these events was also investigated.
Kjell Ohlsson, P. Bjrök
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Scanning for therapeutic targets within the cytokine network of idiopathic inflammatory myopathies [PDF]
, 2015 The idiopathic inflammatory myopathies (IIM) constitute a heterogeneous group of chronic disorders that include dermatomyositis (DM), polymyositis (PM), sporadic inclusion body myositis (IBM) and necrotizing autoimmune myopathy (NAM).
De Paepe, Boel, Zschüntzsch, Jana
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The effects of tumor necrosis factor and interleukin 1 on osseous and soft tissue wound healing [PDF]
, 2002 Thesis (M.S.D.)--Boston University, Henry M. Goldman School of Dental Medicine, 2002 (Endodontics).Includes bibliography (leaves 63-68).The role of inflammatory mediators in surgical repair has not been delineated.
Gillen, Thomas
core
Modulation of Functional Activities of Chicken Heterophils by Recombinant Chicken IFN-γ [PDF]
, 2001 The objective of the present studies was to examine the in vitro effects of recombinant chicken interferon-γ (rChIFN-γ) on shape change, phagocytosis, and the oxidative/nonoxidative killing activities of day-old chicken heterophils.
B. Kaspers +12 more
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Virus-Like Particle-Mediated Vaccination against Interleukin-13 May Harbour General Anti-Allergic Potential beyond Atopic Dermatitis [PDF]
, 2020 Virus-like particle (VLP)-based anti-infective prophylactic vaccination has been established in clinical use. Although validated in proof-of-concept clinical trials in humans, no VLP-based therapeutic vaccination against self-proteins to modulate chronic
Foerster, John, Molęda, Aleksandra
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