Results 271 to 280 of about 991,315 (356)

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source

Interaction of CD99 and its ligands regulates immunoregulatory pathways in NK cells. [PDF]

Front Immunol
Thu MM, Takheaw N, Laopajon W, Kasinrerk W, Pata S.   +4 more
europepmc   +1 more source

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

Advanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin, Shicong Zheng, Pei Song, Jie Chang, Zewei Chen, Cang Li, Min Yu, Lude Wang, Shian Yu   +8 more
wiley   +1 more source

The neuro-immune insights of itch: peripheral mechanisms and central glial contributions. [PDF]

Cell Mol Biol Lett
Li Z, Yu N, Feng S, Wang X, Chu YX, Liu X.   +5 more
europepmc   +1 more source

Oral Prebiotic Polysaccharide Hydrogels Sustaining Colon Antibody Release Alleviate Inflammatory Bowel Disease

Advanced Science, EarlyView.
An orally administered prebiotic polysaccharide hydrogel (predaGel) based on inulin and alginate‐dopamine is stable in the stomach, adheres to the intestine, and degrades slowly in the colon. It enables site‐specific delivery of anti‐TNF‐α and anti‐IL‐12/23 antibodies, scavenges reactive oxygen species, and remodels gut microbiota, offering effective ...
Xinyi Dong, Huan He, Li Cao, Fenghua Meng, Zhiyuan Zhong   +4 more
wiley   +1 more source

The role of interleukins in peripheral nerve injury and the current status of treatment. [PDF]

Front Immunol
Shen Y, Li M, Jin S, Yu Z, Liu Q, Yao H, Jiang Y, Fu J, Li N.   +8 more
europepmc   +1 more source

An intricate relationship between fibrosis and autoimmune diseases: a specific focus on unraveling its molecular, immunological, and epigenetic drivers. [PDF]

Front Immunol
Morey MG, Illanad GH, Rasool M.
europepmc   +1 more source

Opioids regulate the functional state of immune cells and reduce inflammatory cardiac injury: Role of opioid receptors, MRGPRX2, and TLR4. [PDF]

J Biomed Res
Gusakova SV, Sirotina M, Maslov LN, Slidnevskaya AS, Kilin M, Kurbatov BK, Kan A, Derkachev IA, Fu F.   +8 more
europepmc   +1 more source

Biological Signatures of Inflammation Biomarkers Identified Using Data Reduction Methods in Adult Population: A Scoping Review Protocol. [PDF]

Health Sci Rep
Sánchez-Gordón G, Plans-Beriso E, Barahona-López C, Anta B, Millet O, Fernández-Navarro P, Fernández de Larrea-Baz N, Castelló-Pastor A.   +7 more
europepmc   +1 more source