Results 261 to 270 of about 12,580,270 (301)

Characterization of the murine interleukin 5 receptor by using a monoclonal antibody

International Immunology, 1990
Murine interleukin 5 (IL-5), a lymphokine produced by helper T cells, is involved in the regulation of growth and differentiation of B cells and other hematopoietic cells. The receptor for IL-5 has been identified as two cross-linked complexes on T88-M cells (a murine IL-5-dependent early B cell line).
N, Yamaguchi, Y, Hitoshi, S, Mita, Y, Hosoya, Y, Murata, Y, Kikuchi, A, Tominaga, K, Takatsu   +7 more
openaire   +2 more sources

Expression of the murine interleukin-5 receptor on Xenopus laevis oocytes

Biochemical and Biophysical Research Communications, 1990
In this study we describe the use of Xenopus laevis oocytes for the detection of mRNA coding for a murine interleukin-5 (mI15) receptor. When injected with sucrose gradient fractionated polyA+ RNA derived from the murine 115-dependent pre B cell line B13, these oocytes could specifically bind 35S-methionine labeled mI15.
R, Devos, J, Tavernier, G, Plaetinck, J, Van der Heyden, A, Rolink, W, Fiers   +5 more
openaire   +2 more sources

Functional analysis of the interleukin-5 receptor antagonist peptide, AF18748

Cytokine, 2004
AF18748 is a dimeric peptide of 2 x 19 amino acids that specifically binds to the alpha-chain of the human IL-5 receptor (IL-5R), preventing binding of IL-5 and acting as a receptor antagonist. However, the peptide acts by inducing alpha-chain dimerization, and we therefore set out to investigate whether this peptide would have any residual agonist ...
Marcela, Rosas, Iain J, Uings, Cornelli, van Aalst, Jan-Willem J, Lammers, Leo, Koenderman, Paul J, Coffer   +5 more
openaire   +2 more sources

Molecular characterization of the β chain of the murine interleukin 5 receptor

International Immunology, 1991
Interleukin 5 (IL-5) is a multifunctional cytokine that regulates the proliferation and differentiation of hematopoietic cells including B cells and eosinophils. The murine IL-5 acts on target cells via an IL-5 specific high-affinity receptor (Kd approximately 150 pM) that has been proposed to be composed of at least two membrane polypeptide chains ...
S, Mita, S, Takaki, Y, Hitoshi, A G, Rolink, A, Tominaga, N, Yamaguchi, K, Takatsu   +6 more
openaire   +2 more sources

Soluble Interleukin-5 Receptor α-Chain Binding Assays: Use for Screening and Analysis of Interleukin-5 Mutants

Analytical Biochemistry, 1995
Interleukin-5 (IL-5) is a key cytokine for the production, differentiation, and activation of eosinophils. IL-5 is a member of the four helical bundle family of cytokines, and in common with many members of the cytokine family it binds to a heterodimeric receptor composed of a ligand binding alpha-chain and a signal-transducing beta-chain.
M, Banks, P, Graber, A E, Proudfoot, C Y, Arod, B, Allet, A R, Bernard, E, Sebille, M, McKinnon, T N, Wells, R, Solari   +9 more
openaire   +2 more sources

Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease

Circulation Research, 2021

exaly  

Interleukin-5 Receptor

2019
Satoshi Takaki, Yoshiyuki Murata, Akira Tominaga, Kiyoshi Takatsu   +3 more
openaire   +1 more source

Biology and therapeutic potential of interleukin-10

Journal of Experimental Medicine, 2020
Anne O'Garra, Margarida Saraiva, Paulo Vieira   +2 more
exaly  

[Interleukin-5 receptor].

Nihon rinsho. Japanese journal of clinical medicine, 1997
N, Ogata, K, Takatsu
openaire   +1 more source

Interleukin-22: Immunobiology and Pathology

Annual Review of Immunology, 2015
Jarrod Dudakov, Alan Hanash
exaly