Amino acid modulation of the carotid body selectively modulates peripheral chemoreceptor respiratory reflex. [PDF]
Gold OMS +4 more
europepmc +1 more source
Single-Cell Transcriptomic Analysis of Macaque LGN Neurons Reveals Novel Subpopulations. [PDF]
Sun SH, Renshaw KT, Pezaris JS.
europepmc +1 more source
Molecular continuity between axon guidance and synaptic function. [PDF]
Kim S, Cho HJ, Wang IH, Park SJ.
europepmc +1 more source
Contrasting Oviposition Preference Despite Limited Chemosensory Receptor Gene Differentiation in Two Cryptic Anopheles Species. [PDF]
Ambadiang MM +8 more
europepmc +1 more source
Remodeling of the glutamatergic system in the Alzheimer's disease medial temporal lobe and superior temporal gyrus. [PDF]
Wasef M, Kwakowsky A.
europepmc +1 more source
Targeting Ionotropic Glutamate Receptors in the Treatment of Epilepsy
Background: A dysfunction in glutamate neurotransmission is critical for seizure. Glutamate is the major excitatory drive in the cerebral cortex, where seizures occur. Glutamate acts via (i) ionotropic (iGlu) receptors, which are ligand-gated ion channels mediating fast excitatory synaptic transmission; and (ii) G proteins coupled metabotropic (mGlu ...
Francesco Fornai, Roberta Celli
exaly +6 more sources
Ionotropic Receptors (IRs): Chemosensory ionotropic glutamate receptors in Drosophila and beyond [PDF]
Ionotropic Receptors (IRs) are a recently characterized family of olfactory receptors in the fruit fly, Drosophila melanogaster. IRs are not related to insect Odorant Receptors (ORs), but rather have evolved from ionotropic glutamate receptors (iGluRs), a conserved family of synaptic ligand-gated ion channels.
Richard Benton, Vincent Croset
exaly +6 more sources
Variant Ionotropic Glutamate Receptors as Chemosensory Receptors in Drosophila [PDF]
Ionotropic glutamate receptors (iGluRs) mediate neuronal communication at synapses throughout vertebrate and invertebrate nervous systems. We have characterized a family of iGluR-related genes in Drosophila, which we name ionotropic receptors (IRs). These receptors do not belong to the well-described kainate, AMPA, or NMDA classes of iGluRs, and they ...
Leslie B Vosshall +2 more
exaly +7 more sources
Related searches:
Ionotropic glutamate receptors
Current Opinion in Chemical Biology, 1999The glutamate-binding sites of ionotropic glutamate receptors are formed from two extracellular domains of a single subunit. Conformational changes induced by agonist binding produce mechanical processes that are translated into ion gating and receptor desensitization.
Christopher F Bigge
exaly +3 more sources
Mammalian ionotropic glutamate receptors
Current Opinion in Neurobiology, 1993Exciting new milestones in glutamate receptor (GluR) channel research include the following: the cloning of N-methyl-D-aspartate (NMDA) receptors; delineation of molecular determinants for ion flow through glutamate-gated channels; the discovery that Ca2+ permeability of non-NMDA receptor channels is determined by RNA editing; the construction of ...
Wisden, W., Seeburg, P.
openaire +3 more sources

