Results 171 to 180 of about 44,977 (226)

Generalised Hodgkin-Huxley model captures human P2X and AMPA receptor currents. [PDF]

J Physiol
Poshtkohi A, Gulbransen BD.
europepmc   +1 more source

The Role of GABA and Its Receptors in Temporal Lobe Epilepsy. [PDF]

Biomolecules
Sperk G, Pirker S.
europepmc   +1 more source

An emerging role for synaptic Zn²⁺ in substance use disorders. [PDF]

Pharmacol Ther
Solis O, Curry FP, Frangos ZJ, Dunne W, Schoenborn I, Lauer A, Gomez JL, Ventriglia EN, Bonaventura J, Michaelides M.   +9 more
europepmc   +1 more source

Sex differences in AMPA receptor trafficking proteins. [PDF]

Biol Sex Differ
Roberts MY, Briand LA.
europepmc   +1 more source

Emerging Regulatory Mechanisms in Sinoatrial Node Automaticity. [PDF]

J Cell Mol Med
Liu H, Cao Y, Su X.
europepmc   +1 more source

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Ionotropic glutamate receptors

Current Opinion in Chemical Biology, 1999
The glutamate-binding sites of ionotropic glutamate receptors are formed from two extracellular domains of a single subunit. Conformational changes induced by agonist binding produce mechanical processes that are translated into ion gating and receptor desensitization.
openaire   +4 more sources

Mammalian ionotropic glutamate receptors

Current Opinion in Neurobiology, 1993
Exciting new milestones in glutamate receptor (GluR) channel research include the following: the cloning of N-methyl-D-aspartate (NMDA) receptors; delineation of molecular determinants for ion flow through glutamate-gated channels; the discovery that Ca2+ permeability of non-NMDA receptor channels is determined by RNA editing; the construction of ...
Wisden, W., Seeburg, P.
openaire   +3 more sources

Glycine agonism in ionotropic glutamate receptors

Neuropharmacology, 2021
Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that mediate the majority of excitatory neurotransmission in the vertebrate CNS. Classified as AMPA, kainate, delta and NMDA receptors, iGluRs are central drivers of synaptic plasticity widely considered as a major cellular substrate of learning and memory. Surprisingly however, five
Stroebel, David, Mony, Laetitia, Paoletti, Pierre   +2 more
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Molecular Structure of Ionotropic Glutamate Receptors

Current Medicinal Chemistry, 2010
L-glutamate is the major excitatory neurotransmitter in the central nervous system (CNS). Although just a few glutamate receptor ligands have turned out to be clinically useful, primarily because of unfavorable psychotropic side effects, the glutamate system remains an attractive molecular target in the treatment of epilepsy, neurodegenerative diseases
A A, Kaczor, D, Matosiuk
openaire   +2 more sources