Results 171 to 180 of about 560,467 (222)

Inhibitory NK receptor expression associates with altered antimalarial function of γδ T cells. [PDF]

open access: yesPLoS Pathog
Olive ME   +11 more
europepmc   +1 more source

Examining the association between fetal HLA-C, maternal KIR haplotypes and birth weight. [PDF]

open access: yesPLoS Genet
Decina CS   +11 more
europepmc   +1 more source

Killer cell immunoglobulin‐like receptors (KIR) of the African‐origin sabaeus monkey: evidence for recombination events in the evolution of KIR [PDF]

open access: yesEuropean Journal of Immunology, 2005
AbstractKiller cell immunoglobulin (Ig)‐like receptors (KIR) were characterized in the West African sabaeus monkey (Chlorocebus sabaeus) to elucidate the mechanism by which diversity evolves in this family of molecules. Complementary DNA encoding four forms of KIR molecules, including KIR3DL, KIR2DL4, KIR2DL5, and KIR3DH forms, were identified in two ...
Bette Körber
exaly   +3 more sources
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NK cell receptor gene of the KIR family with two IG domains but highest homology to KIR receptors with three IG domains

Tissue Antigens, 1996
The killer cell inhibitory receptors (KIRs) are surface glycoproteins expressed by natural killer (NK) cells and some T cells. They recognize polymorphic human HLA class I molecules. Two families of KIRs have been identified and named p58 and p70. The p58 family of genes encode type I membrane proteins with two extracellular immunoglobulin (Ig) domains,
A, Selvakumar, U, Steffens, B, Dupont
openaire   +2 more sources

Genetic variation, Fcγ receptors, KIRs and infection: the evolution of autoimmunity

Current Opinion in Immunology, 2010
Recent work has emphasised the marked genetic variability that exists in the Fc receptor locus. This variation can contribute to the risk of autoimmune disease in both mice and humans, but can also have a profound impact on defence against infection.
Marion, Espeli   +4 more
openaire   +2 more sources

KIR: Diverse, Rapidly Evolving Receptors of Innate and Adaptive Immunity

Annual Review of Immunology, 2002
KIR genes have evolved in primates to generate a diverse family of receptors with unique structures that enable them to recognize MHC-class I molecules with locus and allele-specificity. Their combinatorial expression creates a repertoire of NK cells that surveys the expression of almost every MHC molecule independently, thus antagonizing the spread of
Carlos, Vilches, Peter, Parham
openaire   +2 more sources

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