Post-translational modification of NK cell receptors offers clues to antigenic specificity riddle. [PDF]
Ustiuzhanina MO +2 more
europepmc +1 more source
Natural killer cells in pediatric HIV cure strategies: from viral control to immunotherapeutics. [PDF]
Cotugno N, de Armas L, Palma P.
europepmc +1 more source
Inhibitory NK receptor expression associates with altered antimalarial function of γδ T cells. [PDF]
Olive ME +11 more
europepmc +1 more source
Examining the association between fetal HLA-C, maternal KIR haplotypes and birth weight. [PDF]
Decina CS +11 more
europepmc +1 more source
Natural killer cells at the interface of tumor immune escape and immunotherapy resistance in endometrial cancer. [PDF]
Poggi A +4 more
europepmc +1 more source
Killer cell immunoglobulin‐like receptors (KIR) of the African‐origin sabaeus monkey: evidence for recombination events in the evolution of KIR [PDF]
AbstractKiller cell immunoglobulin (Ig)‐like receptors (KIR) were characterized in the West African sabaeus monkey (Chlorocebus sabaeus) to elucidate the mechanism by which diversity evolves in this family of molecules. Complementary DNA encoding four forms of KIR molecules, including KIR3DL, KIR2DL4, KIR2DL5, and KIR3DH forms, were identified in two ...
Bette Körber
exaly +3 more sources
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The killer cell inhibitory receptors (KIRs) are surface glycoproteins expressed by natural killer (NK) cells and some T cells. They recognize polymorphic human HLA class I molecules. Two families of KIRs have been identified and named p58 and p70. The p58 family of genes encode type I membrane proteins with two extracellular immunoglobulin (Ig) domains,
A, Selvakumar, U, Steffens, B, Dupont
openaire +2 more sources
Genetic variation, Fcγ receptors, KIRs and infection: the evolution of autoimmunity
Current Opinion in Immunology, 2010Recent work has emphasised the marked genetic variability that exists in the Fc receptor locus. This variation can contribute to the risk of autoimmune disease in both mice and humans, but can also have a profound impact on defence against infection.
Marion, Espeli +4 more
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KIR: Diverse, Rapidly Evolving Receptors of Innate and Adaptive Immunity
Annual Review of Immunology, 2002KIR genes have evolved in primates to generate a diverse family of receptors with unique structures that enable them to recognize MHC-class I molecules with locus and allele-specificity. Their combinatorial expression creates a repertoire of NK cells that surveys the expression of almost every MHC molecule independently, thus antagonizing the spread of
Carlos, Vilches, Peter, Parham
openaire +2 more sources

