Results 191 to 200 of about 15,494 (227)

Killer cell immunoglobulin-like receptor (KIR) locus profiles in the Tunisian population

Human Immunology, 2015
Killer cell immunoglobulin-like receptors (KIRs) are a family of inhibitory and activatory receptors that are expressed by most natural killer (NK) cells. The KIR gene family is polymorphic: genomic diversity is achieved through differences in gene content and allelic polymorphism.
Bani, Meriem, Seket, Jihen, Kaabi, Houda, Cherif, Ghaya, Chaabane, Manel, Bellali, Hedi, Hmida, Slama   +6 more
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Linkage disequilibrium organization of the human KIR superlocus: implications for KIR data analyses [PDF]

Immunogenetics, 2010
An extensive family-based study of linkage disequilibrium (LD) in the killer cell immunoglobulin-like receptors (KIR) cluster was performed. We aimed to describe the LD structure in the KIR gene cluster using a sample of 418 founder haplotypes identified
Pierre-Antoine Gourraud, Ashley Meenagh, Anne Cambon-Thomsen   +2 more
exaly   +2 more sources

14th International HLA and Immunogenetics Workshop: Report on KIR receptors and their applications

Tissue Antigens, 2007
AbstractDuring the last few years many laboratories have developed a keen interest in detecting killer immunoglobulin‐like receptor (KIR) receptor genes in various populations, diseases and in stem cell transplantation. At the 14th International Histocompatibility Workshop held in Melbourne in December 2006, many of these laboratories presented their ...
D, Middleton, F T, Christiansen
openaire   +2 more sources

Receptor-ligand analyses define minimal killer cell Ig-like receptor (KIR) in humans

Immunogenetics, 2006
Interactions between inhibitory killer cell immunoglobulin-like receptors (iKIR) and human leukocyte antigen (HLA) class I molecules regulate natural killer (NK) cell responses to eliminate infected and transformed cells while maintaining tolerance to healthy cells.
Zeying, Du, David W, Gjertson, Elaine F, Reed, Raja, Rajalingam   +3 more
openaire   +2 more sources

Significance of inhibitory maternal killer-cell immunoglobulin-like receptor (KIR) and fetal KIR ligand genotype combinations in placenta related obstetric complications

Journal of Reproductive Immunology, 2021
Some maternal killer-cell immunoglobulin-like receptor (KIR) and fetal KIR ligand genotypes are associated with obstetric complications, such as recurrent miscarriage, fetal growth restriction, preeclampsia, and preterm birth. However, how KIR/KIR ligand genotypes affect these placenta-related obstetric complications has not been fully understood.
Gokcen Orgul, Klara Dalva, Sevim Dalva-Aydemir, Ridvan Goksel Alniacik, Hanife Guler Donmez, Ayse Nur Cakar, Meral Beksac, Mehmet Sinan Beksac   +7 more
openaire   +3 more sources

Killer Immunoglobulin-Like Receptors (KIRs) Genotypes in a Belgian Population.

Blood, 2004
Abstract KIRs (Killer cell Immunoglobulin-like Receptors) are expressed on NK (Natural Killer) cells and a subpopulation of T lymphocytes namely memory CD8+ T cells. The distribution of KIR genes varies among individuals and populations. These genes are encoded on chromosome 19 (19q13.4).
Melanny Hidajat, Dominik Selleslag, Achiel Van Hoof, Jan Van Droogenbroeck, Johan Billiet, Arnold Criel   +5 more
openaire   +1 more source

Report from the Eleventh Killer Immunoglobulin‐like Receptor (KIR) Workshop: Novel insights on KIR polymorphism, ligand recognition, expression and function

HLA, 2019
The Eleventh Killer Immunoglobulin‐like Receptor (KIR) Workshop was held in Camogli (Genoa, Italy) in October 2018. This congress brought together 113 participants working on KIR field. Fifty‐eight studies have been presented, the majority of which included unpublished data. Thus, KIR workshop, allowing the meeting of people sharing their knowledge and
Falco, Michela, Sivori, Simona, Meazza, Raffaella, Pende, Daniela   +3 more
openaire   +2 more sources

Molecular recognition by Ig-like receptors, KIRs and FcγRs

2001
Structural studies by us and other groups have shown that Killer cell Ig-like receptors (KIRs) and Fcγ receptors (FcγR) have a similar, unique topology (intermediate between I set and C2 set). In order to gain further insight into molecular recognition by these receptors, we have used surface plasmon resonance (SPR) to analyze the kinetic and ...
Katsumi Maenaka, P. Anton van der Merwe, David I. Stuart, Peter Sondermann, E. Yvonne Jones   +4 more
openaire   +1 more source

Diversity and association of HLA/KIR receptors with type 2 diabetes in South India

International Journal of Immunogenetics, 2019
AbstractThe present study was undertaken to delineate the association(s) of KIR–HLA combination in South Indian Type 2 diabetes mellitus (T2DM) patients. The T2DM patients (n = 343) and healthy controls (n = 309) were genotyped for KIR/HLA ligands by PCR‐SSP method.
Rathika Chinniah, Murali Vijayan, Ramgopal Sivanadham, Padmamalini Ravi, Dharmarajan Panneerselvam, Arun Kannan, Balakrishnan Karuppiah   +6 more
openaire   +2 more sources

Killer Cell Immunoglobulin-Like Receptor (KIR) Genotypes in Patients with Recurrent Tonsillitis

Genetic Testing, 2008
Aims : This study represents the first report on the distribution of killer cell immunoglobulin-like receptor (KIR) genotype among recurrent tonsillitis patients. We recruited 34 Lebanese pediatric patients diagnosed with recurrent tonsillitis and had their DNA typed using sequence-specific primer technique for ...
Mohamad, Bitar, Roy, Khalaf, Wael, Shamseddeen, Nady, El Hajj, Georges, Ibrahim, Layal, Greige, Ghazi, Zaatari, Nabil, Fuleihan, Amira, Sabbagh, Rami, Mahfouz   +9 more
openaire   +3 more sources