Results 191 to 200 of about 560,467 (222)

Diversity and association of HLA/KIR receptors with type 2 diabetes in South India

International Journal of Immunogenetics, 2019
AbstractThe present study was undertaken to delineate the association(s) of KIR–HLA combination in South Indian Type 2 diabetes mellitus (T2DM) patients. The T2DM patients (n = 343) and healthy controls (n = 309) were genotyped for KIR/HLA ligands by PCR‐SSP method.
Rathika Chinniah, Murali Vijayan, Ramgopal Sivanadham, Padmamalini Ravi, Dharmarajan Panneerselvam, Arun Kannan, Balakrishnan Karuppiah   +6 more
openaire   +2 more sources

Killer Cell Immunoglobulin-Like Receptor (KIR) Genotypes in Patients with Recurrent Tonsillitis

Genetic Testing, 2008
Aims : This study represents the first report on the distribution of killer cell immunoglobulin-like receptor (KIR) genotype among recurrent tonsillitis patients. We recruited 34 Lebanese pediatric patients diagnosed with recurrent tonsillitis and had their DNA typed using sequence-specific primer technique for ...
Mohamad, Bitar, Roy, Khalaf, Wael, Shamseddeen, Nady, El Hajj, Georges, Ibrahim, Layal, Greige, Ghazi, Zaatari, Nabil, Fuleihan, Amira, Sabbagh, Rami, Mahfouz   +9 more
openaire   +3 more sources

Expression cloning of rat cerebellar adenosine A1 receptor by coupling to Kir channels

NeuroReport, 1997
G protein activation of inwardly rectifying K+ (Kir) channels by heptahelical receptors is an important signaling motif in slow synaptic transmission in the mammalian brain. To isolate candidate receptors responsive to the purine nucleoside adenosine, a cerebellar cDNA library was constructed in the vector pSGEM and transcripts were injected into ...
Pfaff, T., Karschin, A.
openaire   +3 more sources

Polymorphisms of killer immunoglobulin-like receptors (KIRs) and HLA ligands in northeastern Thais

Immunogenetics, 2013
Killer cell immunoglobulin-like receptors (KIRs) are cell surface receptors on natural killer (NK) cells and subsets of T cells. The functions of NK cells are partly regulated by interactions between KIRs and HLA ligands on target cells. In this study, the presence or absence of 17 KIR genes and their known HLA ligands have been investigated in 235 ...
Suwit, Chaisri, Kriengkrai, Kitcharoen, Amornrat V, Romphruk, Arunrat, Romphruk, Campbell S, Witt, Chanvit, Leelayuwat   +5 more
openaire   +2 more sources

Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA

Tissue Antigens, 2010
The killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop (IHIWS) sought to explore worldwide population variation in the KIR loci, and to examine the relationship between KIR genes and their human leukocyte antigen (HLA) ligands. Fifteen laboratories submitted KIR genotype and HLA ligand
J A, Hollenbach, A, Meenagh, C, Sleator, C, Alaez, M, Bengoche, A, Canossi, G, Contreras, L, Creary, I, Evseeva, C, Gorodezky, R-A, Hardie, T Hemming, Karlsen, B, Lie, M, Luo, M, Martinetti, C, Navarette, D C M, de Oliveira, G, Ozzella, A, Pasi, E, Pavlova, S, Pinto, L C, Porto, P, Santos, A, Slavcev, D, Srinak, S, Tavoularis, S, Tonks, E, Trachtenberg, S, Vejbaesya, D, Middleton   +29 more
openaire   +2 more sources

Natural Killer Cell Immunoglobulin-like Receptors (KIR) Genotypes in two Arab Populations: Will KIR become a genetic landmark between nations?

Molecular Biology Reports, 2007
Genotypic profiles of the Natural killer cell Immunoglobulin-like Receptors (KIR) have been reported to vary among different ethnic groups and this study represents a comparative report on its distribution between two Arabic populations in the Middle East: Lebanese and Palestinians.
Khazen, Georges, Rayes, Roni, Bazarbachi, Ali, Sabbagh, Amira, Zaatari, Ghazi, Mahfouz, Rami   +5 more
openaire   +3 more sources

Mismatches In Killer Immunoglobulin Receptor (KIR) Ligands and Inhibitory KIR Receptors Between Donor and Recipients Improve Survival After Non T Cell Depleted Haploidentical Transplantation

Blood, 2013
Abstract Introduction Alloreactivity triggered by interaction of Killer immunoglobulin-like receptors (KIRs) on donor Natural killer (NK) cells and their ligands on recipients plays a role in the graft-versus-tumour effect. Different predictive models have been postulated for measuring alloreactivity:
Mariana Bastos-Oreiro, Javier Anguita, Carolina Martínez-Laperche, Almudena Navarro, Lucía Fernandez, Pascual Balsalobre, Cristina Muñoz, Mi Kwon, Ana Perez, Cristina Pascual, Antonio Perez, Ismael Buno, Jorge Gayoso, Jose Luis Díez   +13 more
openaire   +1 more source

Killer Cell Immunoglobulin-Like Receptor (KIR) Genes in the Basque Population: Association Study of KIR Gene Contents With Type 1 Diabetes Mellitus

Human Immunology, 2006
Killer cell immunoglobulin-like receptors (KIR) form a group of regulatory molecules that specifically recognize HLA class I molecules, modulating cytolytic activity of natural killer cells. The number of KIR genes can vary between individuals, significant allelic variations have been described, and KIR genes are organized in a complex and ...
Izortze, Santin, Guiomar Pérez, de Nanclares, Begoña, Calvo, Ayman, Gaafar, Luis, Castaño, Jose Ramon, Bilbao   +5 more
openaire   +2 more sources

The minimal essential KIR receptor in humans

Human Immunology, 2005
Zeying Du, John Muramoto, Elaine F. Reed, Raja Rajalingam   +3 more
openaire   +1 more source

Killer-cell Immunoglobulin-like Receptor (KIR)

Journal of Immunological Methods, 2003
openaire   +1 more source