Results 181 to 190 of about 15,494 (227)

Killer cell immunoglobulin-like receptor (KIR) alleles suggested to be associated with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). [PDF]

open access: yesBrain Behav Immun
Ramadan DJ   +11 more
europepmc   +1 more source

Molecular Interactions Between NK Cells and Acute Leukemic Cells: KIR2DL5 Drastically Limits NK Cell Responses. [PDF]

open access: yesJ Clin Immunol
Ferron E   +17 more
europepmc   +1 more source

Do the expressions of HLA-G and killer cell immunoglobulin-like receptors change in colorectal cancer? [PDF]

open access: yesTurk J Med Sci
Dinçer E   +9 more
europepmc   +1 more source
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NK cell receptor gene of the KIR family with two IG domains but highest homology to KIR receptors with three IG domains

Tissue Antigens, 1996
The killer cell inhibitory receptors (KIRs) are surface glycoproteins expressed by natural killer (NK) cells and some T cells. They recognize polymorphic human HLA class I molecules. Two families of KIRs have been identified and named p58 and p70. The p58 family of genes encode type I membrane proteins with two extracellular immunoglobulin (Ig) domains,
A, Selvakumar, U, Steffens, B, Dupont
openaire   +2 more sources

Genetic variation, Fcγ receptors, KIRs and infection: the evolution of autoimmunity

Current Opinion in Immunology, 2010
Recent work has emphasised the marked genetic variability that exists in the Fc receptor locus. This variation can contribute to the risk of autoimmune disease in both mice and humans, but can also have a profound impact on defence against infection.
Marion, Espeli   +4 more
openaire   +2 more sources

KIR: Diverse, Rapidly Evolving Receptors of Innate and Adaptive Immunity

Annual Review of Immunology, 2002
KIR genes have evolved in primates to generate a diverse family of receptors with unique structures that enable them to recognize MHC-class I molecules with locus and allele-specificity. Their combinatorial expression creates a repertoire of NK cells that surveys the expression of almost every MHC molecule independently, thus antagonizing the spread of
Carlos, Vilches, Peter, Parham
openaire   +2 more sources

Significance of KIR like natural killer cell receptors in autoimmune disorders

Clinical Immunology, 2020
Killer cell immunoglobulin-like receptors (KIRs), act as the regulators for the cytolytic activity of natural killer and certain T cells by interacting with the HLA class I ligands. KIRs have been shown to contribute to the pathogenesis of several autoimmune diseases. However, their specific roles are still not very clear.
Suraksha, Agrawal, Swayam, Prakash
openaire   +2 more sources

Investigation of killer cell immunoglobulin‐like receptor (KIR) gene diversity: KIR2DL2, KIR2DL5 and KIR2DS5

Tissue Antigens, 2008
AbstractHuman killer cell immunoglobulin‐like receptor (KIR) genes are important for restraining natural killer cytotoxicity toward cells with autologous human leukocyte antigen (HLA) while targeting cells lacking or expressing low levels of self‐HLA molecules.
A, Gonzalez   +3 more
openaire   +2 more sources

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