Results 1 to 10 of about 71,229 (198)

Lipoprotein receptor interactions are not required for monocyte oxidation of LDL.

Journal of Lipid Research, 1995
Upon activation, human peripheral blood monocytes and U937 cells oxidized low density lipoprotein (LDL), converting it to a cytotoxin. The oxidized LDL loses its ability to interact specifically with the native LDL (apoB/E) receptor and becomes a ligand ...
M K Cathcart, Q Li, G M Chisolm, 3rd
doaj   +1 more source

ELISA measurement of LDL receptors

Journal of Lipid Research, 1990
An enzyme-linked immunosorbent assay was developed for measurement of low density lipoprotein (LDL) receptors. A monospecific polyclonal antibody to LDL receptor purified from rat liver that reacted with rat, mouse, canine, and human LDL receptor was ...
K May, FB Kraemer, J Chen, AD Cooper
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Low density lipoprotein receptors in rat adipose cells: subcellular localization and regulation by insulin

Journal of Lipid Research, 1994
The distribution of LDL receptors within subcellular compartments of isolated rat adipose cells and the effects of insulin on their expression have been assessed.
F B Kraemer, S A Sather, B Park, C Sztalryd, V Natu, K May, H Nishimura, I Simpson, A D Cooper, S W Cushman   +9 more
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Enhanced clearance from plasma of low density lipoproteins containing a truncated apolipoprotein, apoB-89.

Journal of Lipid Research, 1990
Previously we have reported on a kindred with hypobetalipoproteinemia in which three sisters were found to be compound heterozygotes for two newly described truncated forms of apoB. apoB-40 and apoB-89.
KG Parhofer, A Daugherty, M Kinoshita, G Schonfeld   +3 more
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Isoproterenol decreases LDL receptor expression in rat adipose cells: activation of cyclic AMP-dependent proteolysis

Journal of Lipid Research, 1996
The low density lipoprotein (LDL) receptor is part of a family of proteins that mediate the uptake of lipoproteins into cells. In this paper we have demonstrated the over-expression in E. coli of a rat LDL receptor fusion protein that contains the region
F B Kraemer, V Natu, A Singh-Bist, S Patel, M C Komaromy, S Medicherla, S Azhar, C Sztalryd   +7 more
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Macrophage oxidative modification of low density lipoprotein occurs independently of its binding to the low density lipoprotein receptor

Journal of Lipid Research, 1996
The oxidative modification of low density lipoproteins (LDL) by arterial wall cells is thought to contribute to atherogenesis. Monocyte/macrophages, among other arterial wall cells, oxidatively modify LDL to a form that is recognized by scavenger ...
R K Tangirala, M J Mol, D Steinberg
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Large impact of low concentration oxidized LDL on angiogenic potential of human endothelial cells: a microarray study. [PDF]

PLoS ONE, 2012
Oxidized LDL (ox-LDL) is a key factor in atherogenesis. It is taken up by endothelial cells primarily by ox-LDL receptor-1 (LOX-1). To elucidate transcriptional responses, we performed microarray analysis on human coronary artery endothelial cells ...
Magomed Khaidakov, Sona Mitra, Xianwei Wang, Zufeng Ding, Nalini Bora, Valery Lyzogubov, Francesco Romeo, Steven A Schichman, Jawahar L Mehta   +8 more
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Effects of streptozotocin-induced diabetes on low density lipoprotein receptor expression in rat adipose tissue

Journal of Lipid Research, 1996
Low density lipoprotein (LDL) receptors are found in most cells, including adipose cells. LDL receptors are primarily regulated by cellular cholesterol content. Insulin and insulin deficiency have been reported to have varying effects on LDL receptors in
S Swami, C Sztalryd, F B Kraemer
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Regulation of hepatic cholesterol and lipoprotein metabolism in ethinyl estradiol-treated rats.

Journal of Lipid Research, 1989
The regulation of hepatic cholesterol and lipoprotein metabolism was studied in the ethinyl estradiol-treated rat in which low density lipoprotein (LDL) receptors are increased many fold.
S K Erickson, S Jaeckle, S R Lear, S M Brady, R J Havel   +4 more
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Macrophage colony-stimulating factor differentially regulates low density lipoprotein and transferrin receptors

Journal of Lipid Research, 2004
Endocytosis mediated by both LDL receptors (LDLRs) and transferrin receptors (TfRs) occurs in clathrin-coated pits and requires specific tyrosine-based internalization sequences located in the cytoplasmic domain of these receptors.
Liqin Du, Steven R. Post
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