Results 161 to 170 of about 126,252 (290)

METAB‐HTX: prospective, longitudinal cohort study evaluating cardiac and systemic metabolism after heart transplantation

open access: yesESC Heart Failure, EarlyView.
The METAB‐HTX trial is a prospective cohort study, evaluating cardiac and systemic metabolism among heart transplant recipients. Myocardial function, energetic and metabolism, allograft vasculopathy, allograft rejection, glucometabolism, lipometabolism, liver‐ and kidney function, leucocyte signatures and thromboinflammation will be evaluated ...
Amin Polzin   +21 more
wiley   +1 more source

The transcriptional profile of iron deficiency in patients with heart failure: Heme‐sparing and reduced immune processes

open access: yesEuropean Journal of Heart Failure, EarlyView.
The analysis workflow, findings and potential clinical consequences of iron deficiency in heart failure (HF). From 881 patients with worsening HF, whole blood transcriptome was analysed using the Affymetrix Human Transcriptome Array (HTA) 2.0. Subjects were stratified according to their transferrin saturation (TSAT) levels as iron‐deficient (TSAT <20%)
Niels Grote Beverborg   +17 more
wiley   +1 more source

Clinical and plasma proteomic characterization of heart failure with supranormal left ventricular ejection fraction: An emerging entity of heart failure

open access: yesEuropean Journal of Heart Failure, EarlyView.
Heart failure (HF) with supranormal ejection fraction (HFsnEF) is an unnoticed but emerging entity in HF. This study showed that HFsnEF carries a similarly increased cardiovascular risk as HF with reduced ejection fraction (HFrEF) and distinct structural and proteomic characteristics from HFrEF, warranting a further comprehensive understanding and ...
Yasuhiko Sakata   +19 more
wiley   +1 more source

Heart failure and obesity: Translational approaches and therapeutic perspectives. A scientific statement of the Heart Failure Association of the ESC

open access: yesEuropean Journal of Heart Failure, EarlyView.
Abstract Obesity and heart failure (HF) represent two growing pandemics. In the general population, obesity affects one in eight adults and is linked with an increased risk for HF. Obesity is even more common in patients with HF, where it complicates the diagnosis of HF and is linked with worse symptoms and impaired exercise capacity. Over the past few
Gianluigi Savarese   +28 more
wiley   +1 more source

Exploring the Potential of Liposomal Delivery of Naringenin and Berberine for Browning Adipose Tissue and Obesity Management

open access: yesEuropean Journal of Lipid Science and Technology, EarlyView.
Biocompatible and biodegradable liposomes were developed to encapsulate naringenin (N) and berberine (B), enhancing their stability and bioavailability. Their effects on thermogenesis and browning in 3T3‐L1 preadipocyte cells compared to their free forms were investigated.
Elif Didem Örs Demet   +7 more
wiley   +1 more source

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