Results 181 to 190 of about 122,014 (288)

Atorvastatin enhances LDL receptor-mediated LDL-C uptake and modulates PCSK9 protein expression in pancreatic β-cells. [PDF]

Islets
Zhang Z, Zheng H, Zhang L, Su P, Chen X, Xiang A, Yang J, Guan H, Fan J, Yu Q.   +9 more
europepmc   +1 more source

Allergenicity, Genotoxicity and Subchronic Toxicity Assessment of IgG Binding Protein LT Produced From Aspergillus oryzae

Journal of Applied Toxicology, EarlyView.
ABSTRACT Gastrointestinal health is one of the fastest growing areas in the food and beverage industry, as its importance to overall health and well‐being is becoming increasingly recognized. Immunoglobulins play a key role in protecting the gastrointestinal tract, and nonbovine sources of immunoglobulins (including camel milk, which has a long history
Kirt R. Phipps, Sachin Patel, Kevin Scaife, Toby Holmes, Alica Šoltésová, Sandra Wingaard Thrane, Louise Kristine Vigsnæs, Nigel Baldwin, Christel Jørgensen   +8 more
wiley   +1 more source

Molecular and Pathophysiological Mechanisms Leading to Ischemic Heart Disease in Patients with Diabetes Mellitus. [PDF]

Int J Mol Sci
Juricic S, Klac J, Stojkovic S, Tesic M, Jovanovic I, Aleksandric S, Dobric M, Zivkovic S, Maricic B, Simeunovic D, Lasica R, Dikic M, Banovic M, Beleslin B.   +13 more
europepmc   +1 more source

Illuminating Immunity: A Systematic Review of Immune Cell Autofluorescence

Journal of Biophotonics, EarlyView.
ABSTRACT Immunophenotyping provides valuable prognostic and diagnostic information, but is technically complex and expensive. The assessment of autofluorescence is label‐free and provides complex information on cell identity. However, research on its application to immunophenotyping has been heterogenous.
Aline Knab, Caroline Giardina, Shane T. Grey, Ewa M. Goldys, Jared M. Campbell   +4 more
wiley   +1 more source

Evinacumab for children with homozygous familial hypercholesterolemia: a plain language summary. [PDF]

Future Cardiol
Wiegman A, Pordy R.
europepmc   +1 more source

LJ-1888, a selective antagonist for the A3 adenosine receptor, ameliorates the development of atherosclerosis and hypercholesterolemia in apolipoprotein E knock-out mice [PDF]

, 2018
Jeong, Lak Shin, Jeong, Se-Jin, Kim, Gyudong, Oh, Goo Taeg, Park, Jong-Gil, Yu, Jinha   +5 more
core   +1 more source

Introducing Two Novel Indices for Evaluating Coronary Artery Stenosis: Athero‐Inflammatory Index and Athero‐Inflammatory Glucose Index

Journal of Clinical Laboratory Analysis, EarlyView.
In this study, we introduced and investigated two novel indices named athero‐inflammatory (AI) index and athero‐inflammatory glucose (AIG) index with coronary stenosis among a total of 2326 participants (761 angiography (+), 406 angiography (−) and 1159 controls) in Mashhad. We found that AI index and AIG index were better and more reliable markers for
Rana Kolahi Ahari, Mohsen Moohebati, Mohammad Tajfard, Habibollah Esmaily, Gordon Ferns, Majid Ghayour‐Mobarhan, Sara Saffar Soflaei   +6 more
wiley   +1 more source

Association of dietary phytochemical index with metabolic markers, serum asymmetric dimethylarginine and atherogenic indices in patients with polycystic ovary syndrome. [PDF]

Nutr Metab (Lond)
Amirkhizi F, Taghizadeh M, Hamedi-Shahraki S, Asghari S.   +3 more
europepmc   +1 more source

Indication‐Specific Dosing and Dose‐Evaluation Strategies in New Indications for Non‐Oncology Monoclonal Antibodies

The Journal of Clinical Pharmacology, EarlyView.
Abstract Compared to traditional small molecule drugs, monoclonal antibodies (mAbs) often display more complex pharmacokinetic (PK) and pharmacodynamic (PD) properties that may be impacted by disease‐specific factors. For mAbs in non‐oncology indications, where the same drug might be used for conditions involving different organ systems and/or having ...
Sherouk M. Tawfik, Fei Tang
wiley   +1 more source

Human macrophage pro-inflammatory polarization in response to free cholesterol and cholesterol remnants. [PDF]

Physiol Rep
Karel P, Barbora M, Hana B, Jan M, Libor J, Jiri F, Sona K, Ivana KL, Rudolf P.   +8 more
europepmc   +1 more source