Results 231 to 240 of about 2,478,316 (288)

Resveratrol improved atherosclerosis by increasing LDLR levels via the EGFR-ERK1/2 signaling pathway. [PDF]

open access: yesLipids Health Dis
Hu D   +8 more
europepmc   +1 more source

Long-term safety and effectiveness of evinacumab in people with homozygous familial hypercholesterolemia: a plain language summary. [PDF]

open access: yesFuture Cardiol
Gaudet D   +18 more
europepmc   +1 more source

HDL-Cholesterol and Triglycerides Dynamics: Essential Players in Metabolic Syndrome. [PDF]

open access: yesAntioxidants (Basel)
Alcover S   +4 more
europepmc   +1 more source

Scavenger Receptors, Oxidized LDL, and Atherosclerosis

Annals of the New York Academy of Sciences, 2001
Abstract: Oxidized LDL (OxLDL) competes with oxidatively damaged and apoptotic cells for binding to mouse peritoneal macrophages, implying the presence of one or more common domains. However, the nature of the ligands involved has not been determined.
Joseph L. Witztum   +12 more
openaire   +4 more sources

Lowering LDL cholesterol, but not raising LDL receptor activity, by ezetimibe [PDF]

open access: possibleJournal of Clinical Lipidology, 2013
Ezetimibe, an inhibitor of intestinal cholesterol absorption, is effective in lowering serum low-density lipoprotein (LDL) cholesterol with or without coadministration of statin. Ezetimibe-plus-statin therapy enhances LDL receptor activity, but it is still unclear whether ezetimibe alone enhances LDL receptor activity, resulting in LDL cholesterol ...
Mitsunobu Kawamura, Hiroshi Hayashi
openaire   +2 more sources

LDL Receptor's β-Propeller Displaces LDL [PDF]

open access: possibleScience, 2002
The low density lipoprotein receptor (LDLR) binds to lipoprotein extracellularly and releases it in the endosome. In his Perspective, Innerarity discusses new structural work (Rudenkoet al.) that shows that an interdomain interaction that occurs at low pH likely displaces ligand from the receptor in the endosome.
openaire   +1 more source

Role of leukocyte-specific LDL receptors on plasma lipoprotein cholesterol and atherosclerosis in mice.

Arteriosclerosis, Thrombosis and Vascular Biology, 1997
Bone marrow-derived macrophages and lymphocytes express LDL receptors (LDL-R), which allow these cells to take up cholesterol-rich lipoproteins. Although these cells are ubiquitously distributed in the body, it is not known whether they influence plasma ...
W. Boisvert, J. Spangenberg, L. Curtiss
semanticscholar   +1 more source

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