Results 111 to 120 of about 2,401,298 (264)

The Impact of Metabolic Complications in Pregnancy on Later Life Maternal Cardiometabolic Health: Findings From the ROLO Longitudinal Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To explore associations between pregnancy metabolic complications and maternal cardiometabolic health 10 years postpartum. Design Prospective Longitudinal Cohort Study following a randomised controlled trial. Setting Single‐centre. Population Pregnancy metabolic complication (pregnancy‐induced hypertension, impaired glucose tolerance,
Kristyn Dunlop, Sophie Callanan, Kaat Philippe, Catherine McNestry, Alexander Douglass, Ricardo Segurado, Rachel K. Crowley, Patrick J. Twomey, Catherine M. Phillips, Fionnuala M. McAuliffe   +9 more
wiley   +1 more source

Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity

Periodontology 2000, EarlyView., 2023
Abstract Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that represent a burden to health‐care systems worldwide as they can only be controlled rather than cured; hence, they require long‐term care. With the exponential increase in NCDs, the occurrence of individuals presenting with more than one chronic disease is ...
Crystal Marruganti, Jean E. Suvan, Francesco D'Aiuto   +2 more
wiley   +1 more source

Prenatal Environmental Hypoxia Enhances Adult Hypoxia Tolerance in Brandt's Voles (Lasiopodomys brandtii): Behavioral and Transcriptomic Insights

Integrative Zoology, EarlyView.
Prenatal hypoxia enhances adult hypoxia tolerance in Brandt's voles, preserving cognitive and memory functions. Transcriptomic analysis reveals adaptive changes in energy metabolism, oxygen transport, and neuroprotective mechanisms, highlighting developmental plasticity.
Mengyang Li, Congcong Qiao, Xiujuan Li, Maolin Huang, Zhenlong Wang, Luye Shi   +5 more
wiley   +1 more source

Inhibition of leptin gene expression and secretion by silibinin: possible role of estrogen receptors

Cytotechnology (Dordrecht), 2012
Kazem Nejati-Koshki, N. Zarghami, Mohammad Pourhassan-Moghaddam, M. Rahmati-Yamchi, Mahdie Mollazade, Marzieh Nasiri, R. J. Esfahlan, A. Barkhordari, Hamid Tayefi-nasrabadi   +8 more
semanticscholar   +1 more source

Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice

Allergy, EarlyView.
Diet‐induced obesity increases transepidermal water loss and compromises barrier function through downregulation of tight junctions and desmosomes. During obesity, MC903 elicits a mixed Th1/2/17 immune response in the skin leading to aggravated ear swelling.
Alicia Martinek, Andrea Deinzer, Roman G. Gerlach, Jana Petzold, Lea Semmler, Christof Vorsatz, Padraic G. Fallon, Christian Schwartz   +7 more
wiley   +1 more source

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors.

Proceedings of the National Academy of Sciences of the United States of America, 1996
H. Baumann, K. Morella, David W. WHITEt, Marlene Dembskii, P. Bailon, Hongkyun Kim, Chun-fai Lai, Louis A. TARTAGLIAt   +7 more
semanticscholar   +1 more source

Control of Blood Pressure, Appetite, and Glucose by Leptin in Mice Lacking Leptin Receptors in Proopiomelanocortin Neurons

HYPERTENSION, 2011
Jussara M. do Carmo, A. D. da Silva, Z. Cai, Shuying Lin, J. Dubinion, J. Hall   +5 more
semanticscholar   +1 more source

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index

Andrology, EarlyView.
Abstract Background The constitutive Leydig cell hormone insulin‐like peptide 3 (INSL3) is considered a good estimate of the adult Leydig cell functional capacity and appears to remain relatively consistent throughout adult male life, only gradually declining into old age.
Richard Ivell, Bilal Tulumcu, Waleed Alhujaili, Ravinder Anand‐Ivell   +3 more
wiley   +1 more source

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.

Proceedings of the National Academy of Sciences of the United States of America, 1997
H. Fei, H. Okano, C. Li, G. Lee, C. Zhao, R. Darnell, J. Friedman   +6 more
semanticscholar   +1 more source