Results 161 to 170 of about 90,104 (295)

Obesity, Leptin and Leptin Receptors

Gene, Cell and Tissue, 2016
Maryam Shojaee, Saeed Khosropour, Peyman Lotfi   +2 more
openaire   +2 more sources

A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury

Neuroprotection, EarlyView.
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley   +1 more source

Visceral adipose tissue according to magnetic resonance imaging as a factor associated with leptin resistance in stable coronary artery disease

Кардиоваскулярная терапия и профилактика
Aim. To evaluate quantitative and radiomic characteristics of abdominal vis­ceral adipose tissue (VAT) using magnetic resonance imaging (MRI), their relationship with lipid, carbohydrate metabolism, inflammation in pa­tients with coronary artery disease (
N. I. Ryumshina, О. A. Koshelskaya, N. V. Naryzhnaya, O. A. Kharitonova, E. S. Kravchenko, K. V. Zavadovsky   +5 more
doaj   +1 more source

Phytochemical Nanoparticles for the Treatment of Neurological Disorders

Phytochemical Analysis, EarlyView.
ABSTRACT Neurological disorders impose a significant burden on the healthcare systems. The latest published data by WHO indicated that stroke was the second leading cause of death globally in 2020, with Alzheimer's disease (AD) and other dementias in the seventh position.
Touraj Ehtezazi, Satyajit D. Sarker
wiley   +1 more source

Fabricating Microfluidic Co‐Cultures of Immortalized Cell Lines Uncovers Robust Design Principles for the Simultaneous Formation of Patterned, Vascularized, and Stem Cell‐Derived Adipose Tissue

Small, EarlyView.
Murphy et al present an optimized co‐culture protocol for immortalized cell line vasculogenesis. Here, immortalized co‐cultures form reproducible microvessel networks across 31‐days, while gradient microchips enable simultaneous mesenchymal stem cell (MSC) adipogenesis and endothelial cell (EC) vasculogenesis.
Ashley R. Murphy, Rose Ann Franco, Mark C. Allenby   +2 more
wiley   +1 more source

Modeling Adipokine and Insulin‐Mediated Crosstalk Between Adipocytes and Beta Cells Using Flow‐Enabled Microfluidics

Small, EarlyView.
A microfluidic system with a µTesla pump is developed to model adipocyte–beta cell crosstalk under flow. Elevated glucose and insulin enhanced adipocyte secretion of IL‐6, TNF‐α, and adiponectin, while IL‐6 stimulated beta‐cell insulin secretion. This feed‐forward loop mimics obesity‐driven beta cell dysfunction, offering new insights into Type 2 ...
Mohamad Orabi, Mehdi Sh Yeganeh, Tae‐Hwa Chun, Joe Fujiou Lo   +3 more
wiley   +1 more source

New Frontiers in Gut Nutrient Sensor Research: Nutrient Sensors in the Gastrointestinal Tract: Modulation of Sweet Taste Sensitivity by Leptin

Journal of Pharmacological Sciences, 2010
The ability to perceive sweet compounds is important for animals to detect an external carbohydrate source of calories and has a critical role in the nutritional status of animals.
Nao Horio, Masafumi Jyotaki, Ryusuke Yoshida, Keisuke Sanematsu, Noriatsu Shigemura, Yuzo Ninomiya   +5 more
doaj  

Emerging Nanonutraceuticals against Obesity

Small Science, EarlyView.
This overview comprehensively compiles the latest research advancements in diversiform nanonutraceuticals against obesity. These nanonutraceuticals are derived from the nanomodifications of some carbohydrates, lipids, proteins, vitamins, minerals, and phytochemicals.
Linjie Ni, Minmin Peng, Yiying Liang, Xiwen Ye, Hanying Zheng, Dongbei Guo, Liang Yang, Xusangni Li, Ronghe Chen   +8 more
wiley   +1 more source

Gut Microbiota as a Mediator Between Intestinal Fibrosis and Creeping Fat in Crohn's Disease

United European Gastroenterology Journal, EarlyView.
ABSTRACT Intestinal stricture remains one of the most challenging complications in Crohn's disease, and its underlying mechanisms are poorly understood. Accumulating evidence suggests that gut microbiota is significantly altered in stenotic intestines and may play a key role in the development of fibrogenesis in Crohn's disease.
Caiguang Liu, Rongchang Li, Jing Nie, Jinshen He, Zihao Lin, Xiaomin Wu, Jinyu Tan, Zishan Liu, Longyuan Zhou, Xiaozhi Li, Zhirong Zeng, Minhu Chen, Shixian Hu, Yijun Zhu, Ren Mao   +14 more
wiley   +1 more source

Key Predictors of Relevant Weight Loss in Patients With Metabolic Dysfunction‐Associated Steatotic Liver Disease

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background and Aims Weight loss is an effective therapeutic strategy for patients with metabolic dysfunction‐associated steatotic liver disease (MASLD). This study aimed to identify factors that predict relevant weight loss, defined as at least 7% of initial body weight, in MASLD outpatients.
Nicola Pugliese, Ivan Arcari, Federica Cerini, Rosa Lombardi, Federica Turati, Grazia Pennisi, Matteo Soleri, Simone Rocchetto, Diletta De Deo, Michele Sagasta, Chiara Masetti, Anna Ludovica Fracanzani, Salvatore Petta, Carlo La Vecchia, Mauro Viganò, Alessio Aghemo   +15 more
wiley   +1 more source