Results 11 to 20 of about 3,169 (190)

Lysophospholipid receptors: Signalling, pharmacology and regulation by lysophospholipid metabolism

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2007
The lysophospholipids, sphingosine-1-phosphate (S1P), lysophosphatidic acid (LPA), sphingosylphosphorylcholine (SPC) and lysophosphatidylcholine (LPC), activate diverse groups of G-protein-coupled receptors that are widely expressed and regulate decisive cellular functions.
Meyer zu Heringdorf, Dagmar, Jakobs, Karl H.   +1 more
openaire   +3 more sources

Lysophospholipid (LPA) receptors in GtoPdb v.2021.3

IUPHAR/BPS Guide to Pharmacology CITE, 2021
Lysophosphatidic acid (LPA) receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Lysophospholipid Receptors [55, 19, 82, 129]) are activated by the endogenous phospholipid LPA. The first receptor, LPA1, was identified as ventricular zone gene-1 (vzg-1) [40], This discovery represented the beginning of the de-orphanisation of members of ...
Valerie P. Tan, Manisha Ray, Tony Ngo, Yasuyuki Kihara, Deepa Jonnalagadda, Danielle Jones, Jerold Chun, Victoria Blaho   +7 more
core   +6 more sources

Human neural progenitors express functional lysophospholipid receptors that regulate cell growth and morphology [PDF]

BMC Neuroscience, 2008
Background Lysophospholipids regulate the morphology and growth of neurons, neural cell lines, and neural progenitors. A stable human neural progenitor cell line is not currently available in which to study the role of lysophospholipids in human neural ...
Callihan Phillip, Sturkie Carla, Machacek David W, Mumaw Jennifer, Hurst Jillian H, Stice Steve L, Hooks Shelley B   +6 more
doaj   +2 more sources

Lysophospholipid (S1P) receptors in GtoPdb v.2023.1

IUPHAR/BPS Guide to Pharmacology CITE, 2023
Sphingosine 1-phosphate (S1P) receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Lysophospholipid receptors [96]) are activated by the endogenous lipid sphingosine 1-phosphate (S1P). Originally cloned as orphan members of the endothelial differentiation gene (edg) family [16, 123], the receptors are currently designated as S1P1R ...
Yasuyuki Kihara, Deepa Jonnalagadda, Danielle Jones, Deron Herr, Jerold Chun, Victoria Blaho   +5 more
openaire   +3 more sources

Lysophospholipid receptors LPA1–3 are not required for the inhibitory effects of LPA on mouse retinal growth cones

Eye and Brain, 2010
Eric Birgbauer, Jerold ChunDepartment of Molecular Biology, Helen L Dorris Institute for Neurological and Psychiatric Disorders, The Scripps Research Institute, La Jolla, CA, USA Abstract: One of the major requirements in the development of the visual ...
Eric Birgbauer, Jerold Chun
doaj   +1 more source

Lysophospholipid (LPA) receptors in GtoPdb v.2023.1

IUPHAR/BPS Guide to Pharmacology CITE, 2023
Lysophosphatidic acid (LPA) receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Lysophospholipid Receptors [62, 23, 91, 144]) are activated by the endogenous phospholipid LPA. The first receptor, LPA1, was identified as ventricular zone gene-1 (vzg-1) [46], This discovery represented the beginning of the de-orphanisation of members of ...
Valerie P. Tan, Manisha Ray, Tony Ngo, Yasuyuki Kihara, Jerold Chun   +4 more
openaire   +3 more sources

From Classical to Alternative Pathways of 2-Arachidonoylglycerol Synthesis: AlterAGs at the Crossroad of Endocannabinoid and Lysophospholipid Signaling

Molecules
2-arachidonoylglycerol (2-AG) is the most abundant endocannabinoid (EC), acting as a full agonist at both CB1 and CB2 cannabinoid receptors. It is synthesized on demand in postsynaptic membranes through the sequential action of phosphoinositide-specific ...
Fabienne Briand-Mésange, Isabelle Gennero, Juliette Salles, Stéphanie Trudel, Lionel Dahan, Jérôme Ausseil, Bernard Payrastre, Jean-Pierre Salles, Hugues Chap   +8 more
doaj   +2 more sources

Lysophospholipid Growth Factors and Their G Protein-Coupled Receptors in Immunity, Coronary Artery Disease, and Cancer [PDF]

The Scientific World Journal, 2002
The physiological lysophospholipids (LPLs), exemplified by lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P), are omnific mediators of normal cellular proliferation, survival, and functions.
Edward J. Goetzl, Markus Graeler, Mei-Chuan Huang, Geetha Shankar   +3 more
doaj   +2 more sources

Lysophospholipid (S1P) receptors in GtoPdb v.2025.3

IUPHAR/BPS Guide to Pharmacology CITE
Sphingosine 1-phosphate (S1P) receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Lysophospholipid receptors [98]) are activated by the endogenous lipid sphingosine 1-phosphate (S1P). Originally cloned as orphan members of the endothelial differentiation gene (edg) family [16, 125], the receptors are currently designated as S1P1R ...
Victoria Blaho, Jerold Chun, Deron R. Herr, Danielle Jones, Yasuyuki Kihara   +4 more
openaire   +2 more sources

The Effect of Different Lysophospholipid Levels on Blood and Milk Biochemical Parameters, Liver and Rumen Enzymes, and Rumen Microbial Population in Early Lactation of Holstein Dairy Cows [PDF]

پژوهشهای تولیدات دامی
Extended Abstract Background: High-yielding cows, especially at the beginning of the lactation period, are mainly in a negative energy balance. This problem occurs due to energy consumption less than the requirements for high production, which causes the
Matin Movagharnezhad, Yadollah Chashnidel, Asadollah Teymouri Yansari, Mohsen Gholizadeh   +3 more
doaj   +1 more source