Results 1 to 10 of about 28,619 (164)
Glycine Release Is Upregulated by Metabotropic Glutamate Receptor 1 in Mouse Hippocampus [PDF]
BiomedicinesBackground/Objectives: The neurotransmitter glycine is involved in several physiological and pathological conditions in the Central Nervous System. Different biological structures, including glycine receptors and transporters, are under study as targets ...
Luca Raiteri +3 more
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Membranes, 2022 Metabotropic glutamate receptors (mGluRs) are membrane receptors that play a central role in the modulation of synaptic transmission and neuronal excitability and whose dysregulation is implicated in diverse neurological disorders.
Brice Miller +3 more
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Expression of GABAAα1, GABAB1, and mGluR2 receptors in the lateral geniculate body of male neonates born to diabetic rats [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Diabetes during gestation is one of the most common pregnancy complications and has adverse effects on offspring, including a negative impact on the offspring’s central nervous system (CNS).
Nasim Alipour +6 more
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Astrocyte Glutamate Uptake and Signaling as Novel Targets for Antiepileptogenic Therapy
Frontiers in Neurology, 2020 Astrocytes regulate and respond to extracellular glutamate levels in the central nervous system (CNS) via the Na+-dependent glutamate transporters glutamate transporter-1 (GLT-1) and glutamate aspartate transporter (GLAST) and the metabotropic glutamate ...
Allison R. Peterson, Devin K. Binder
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Kinetic fingerprinting of metabotropic glutamate receptors
Communications Biology, 2023 FRET and confocal patch-clamp fluorometry in oocytes is used to analyze glutamateinduced conformational changes and dimerization of mGluR 1-8 homo- and heterodimers.
Taulant Kukaj +4 more
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Simulation of postsynaptic glutamate receptors reveals critical features of glutamatergic transmission. [PDF]
PLoS ONE, 2011 Activation of several subtypes of glutamate receptors contributes to changes in postsynaptic calcium concentration at hippocampal synapses, resulting in various types of changes in synaptic strength.
Renaud Greget +13 more
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The Hippocampus Is the Place to Be: Opioid Receptors and LTP
Cell Reports, 2019 Nam et al. (2019) genetically modulate the expression of astrocytic μ-opioid receptors to reveal they are necessary for drug-induced conditioned place preference.
Thomas M. Sanderson +3 more
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The Role of Glutamate Receptors in Epilepsy
Biomedicines, 2023 Glutamate is an essential excitatory neurotransmitter in the central nervous system, playing an indispensable role in neuronal development and memory formation. The dysregulation of glutamate receptors and the glutamatergic system is involved in numerous
Tsang-Shan Chen +3 more
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eLife, 2020 Metabotropic glutamate receptors (mGluRs) play an important role in synaptic plasticity and memory and are largely classified based on amino acid sequence homology and pharmacological properties.
Ananya Dasgupta +7 more
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The DLGAP family: neuronal expression, function and role in brain disorders
Molecular Brain, 2017 The neurotransmitter glutamate facilitates neuronal signalling at excitatory synapses. Glutamate is released from the presynaptic membrane into the synaptic cleft.
Andreas H. Rasmussen +2 more
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