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Immunoexcitoxicity as the possible major pathophysiology behind multiple sclerosis and other autoimmune disorders. [PDF]

Surg Neurol Int
Blaylock RL.
europepmc   +1 more source

ATP and glutamate coordinate contractions in the freshwater sponge Ephydatia muelleri.

J Exp Biol
Ho VR, Goss GG, Leys SP.
europepmc   +1 more source

Inhibition of metabotropic glutamate receptor-5 alleviates hepatic steatosis by enhancing autophagy <i>via</i> activation of the AMPK signaling pathway. [PDF]

World J Gastroenterol
Tao M, Zhang LL, Zhou GH, Wang C, Luo X.
europepmc   +1 more source

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Metabotropic glutamate receptors

Cell and Tissue Research, 2006
Metabotropic glutamate receptors (mGlus) are a family of G-protein-coupled receptors activated by the neurotransmitter glutamate. Molecular cloning has revealed eight different subtypes (mGlu1-8) with distinct molecular and pharmacological properties. Multiplicity in this receptor family is further generated through alternative splicing. mGlus activate
Ferraguti F., Shigemoto R.
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Metabotropic glutamate receptors

Amino Acids, 2007
l-Glutamate, one of the main neurotransmitters in the central nervous system (CNS), acts on two groups of receptors: (a) a group of ionotropic receptors that includes N-methyl-d-aspartate (NMDA), α-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA), and kainate receptors, and (2) a group of metabotropic receptors (mGluRs).
Andrzej Pilc, Krystyna Ossowska
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Structure of the metabotropic glutamate receptor

Current Opinion in Neurobiology, 2003
In the twelve years since the molecular elucidation of the metabotropic glutamate receptor subtype 1, a class III family of G-protein-coupled receptors has emerged; members of this family include the calcium-sensing receptor, the GABA(B) receptor, some odorant receptors and some taste receptors.
Shigetada Nakanishi, Hisato Jingami, Kosuke Morikawa   +2 more
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Metabotropic Glutamate Receptors and Neurodegeneration

2004
Metabotropic glutamate (mGlu) receptors, which exert a modulatory effect on excitatory synaptic transmission, are considered as potential targets for neuroprotective drugs and the advent of potent and centrally available subtype-selective ligands has lead to an extensive investigation of the role of individual mGlu receptor subtypes in ...
BRUNO, Valeria Maria Gloria, BATTAGLIA, Giuseppe, A. Copani, G. Casabona, M. Storto, V. D. Giorgi, R. Ngomba, NICOLETTI, Ferdinando   +7 more
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