Results 61 to 70 of about 115,612 (189)
Dopamine and N-Methyl-D- Aspartate Receptor Interactions in the Neostriatum [PDF]
Developmental Neuroscience, 1998 This review examines dopamine (DA) and glutamate receptor interactions in the neostriatum (NS) primarily from a neurophysiological perspective. Historically, a clear understanding of the function of DA in the NS has been difficult because it was considered a classical neurotransmitter with either excitatory or inhibitory actions and because many of the
Carlos Cepeda, Michael Levine
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Journal of Pharmacological Sciences, 2008 Recent studies indicate that an endogenous co-agonist for an N-methyl-D-aspartate (NMDA) receptor–related glycine site, D-serine, is synthesized by serine racemase and is metabolized by D-amino acid oxidase (DAO) and that acute treatment with morphine ...
Masanobu Yoshikawa +7 more
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Nature Communications, 2021 N-Methyl-D-aspartate receptors (NMDARs) activation involves closure of the GluN1 and GluN2 subunit ligand binding domains, which is regulated allosterically by the amino-terminal domain (ATD).
Vojtech Vyklicky +3 more
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A via receptor NMDA-óxido nítrico-GMP cíclico como alvo para o desenvolvimento de medicações antipsicóticas não-dopaminérgicas para a esquizofrenia [PDF]
, 2011 Schizophrenia is a devastating disorder that occurs in about 1% of the population worldwide. For over 30 years, it has been considered to be the result of dysfunctional brain dopaminergic pathways.
BAKER, Glen B. +5 more
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Selective vulnerabilities of N-methyl-D-aspartate (NMDA) receptors during brain aging
Frontiers in Aging Neuroscience, 2010 N-methyl-D-aspartate (NMDA) receptors are present in high density within the cerebral cortex and hippocampus and play an important role in learning and memory.
Brenna L Brim, Siba R Das
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Spermine regulates N-methyl-d-aspartate receptor desensitization
Neuron, 1992 The action of the endogenous polyamine spermine on NMDA-induced responses (in the presence of glycine) was evaluated in cultured spinal cord neurons under voltage- and concentration-clamp conditions. Spermine potentiated NMDA-induced responses in a dose-dependent manner.
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Neural Regeneration ResearchThe involvement of the excitatory amino acids glutamate and aspartate in cerebral ischemia and excitotoxicity is well-documented. Nevertheless, the role of non-excitatory amino acids in brain damage following a stroke or brain trauma remains largely ...
Victoria Jiménez Carretero +4 more
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Potassium channel activators protect the N-methyl-D-aspartate-induced cerebral vascular dilation after combined hypoxia and ischemia in piglets [PDF]
, 1998 Background and Purpose-Cerebral arteriolar dilation to N-methyl-D-aspartate (NMDA) is a neuronally mediated multistep process that is sensitive to cerebral hypoxia and ischemia (H/I).
Bari, Ferenc +2 more
core
Update in the research of anti-N-methyl-D-aspartate receptor encephalitis
Chinese Journal of Contemporary Neurology and Neurosurgery, 2014 doi: 10.3969/j.issn.1672-6731.2014.08 ...
Jia-wei WANG
doaj
ON or OFF?: Modulating the N-Methyl-D-Aspartate Receptor in Major Depression [PDF]
Frontiers in Molecular Neuroscience, 2017 Since the discovery that a single dose of ketamine, an N-methyl-D-aspartate receptor (NMDAR) antagonist, had rapid and long-lasting antidepressant effects, there has been increased interest in using NMDAR modulators in the pharmacotherapy of depression.
Chan, S, Matthews, E, Burnet, P
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