Results 51 to 60 of about 454,469 (213)
Frontiers in Molecular Neuroscience, 2014 The classic neurotrophins Nerve Growth Factor (NGF), Brain Derived Neurotrophic Factor (BDNF) and Neurotrophins NT-3 and NT-4 are well known to regulate various aspects of neuronal differentiation, survival and growth.
Rachel eUren, Ann eTurnley
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Current Pharmacologic Approaches in Painful Bladder Research: An Update [PDF]
International Neurourology Journal, 2017 The symptoms of interstitial cystitis (IC)/bladder pain syndrome (BPS) may have multiple causes and involve many contributing factors. Traditional treatments (intravesical instillations) have had a primary focus on the bladder as origin of symptoms ...
Karl-Erik Andersson, Lori Birder
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Nerve growth factor receptors on normal and injured sensory neurons
Journal of Neuroscience, 1989 The density and binding properties of receptors for nerve growth factor (NGF) in normal and injured sensory neurons have been analyzed by quantitative radioautography following incubation of tissue sections with radioiodinated NGF.
V. Verge, R. RIOPELLE', P. Richardson
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Targeting nerve growth factor: an Achilles’ heel for tumors?
Journal for ImmunoTherapy of CancerA tumor’s ability to attract innervation is a critical factor in tumor progression and immune escape, with the sympathetic nervous system playing a major role.
Elizabeth Repasky, Hemn Mohammadpour
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Modeling Glioma Growth and Invasion in Drosophila melanogaster
Neoplasia: An International Journal for Oncology Research, 2009 Glioblastoma is the most common and most malignant intrinsic human brain tumor, characterized by extensive invasion and proliferation of glial (astrocytic) tumor cells, frequent activation of tyrosine kinase receptor signaling pathways, relative ...
Hanna Teresa Witte +3 more
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Nerve Growth Factor-Regulated Emergence of Functional Delta-Opioid Receptors
Journal of Neuroscience, 2010 Sorting of intracellular G-protein-coupled receptors (GPCRs) either to lysosomes for degradation or to plasma membrane for surface insertion and functional expression is a key process regulating signaling strength of GPCRs across the plasma membrane in ...
B. Bie +8 more
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FGF5 Regulates Schwann Cell Migration and Adhesion
Frontiers in Cellular Neuroscience, 2020 The fibroblast growth factor (FGF) family polypeptides play key roles in promoting tissue regeneration and repair. FGF5 is strongly up-regulated in Schwann cells of the peripheral nervous system following injury; however, a role for FGF5 in peripheral ...
Bing Chen +7 more
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Journal of Biological Chemistry, 2009 Nerve growth factor (NGF) is produced as a precursor called pro-nerve growth factor (proNGF), which is secreted by many tissues and is the predominant form of NGF in the central nervous system.
R. Masoudi +8 more
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Molecular Pain, 2018 Subcutaneous formalin injections are used as a model for tissue injury-induced pain where formalin induces pain and inflammation indirectly by crosslinking proteins and directly through activation of the transient receptor potential A1 receptor on ...
Elín I Magnúsdóttir +5 more
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Molecular characteristics of nerve growth factor receptors on PC12 cells.
Journal of Biological Chemistry, 1985 Cross-linking of 125I-nerve growth factor (NGF) to PC12 cells with the photoreactive heterobifunctional agent N-hydroxysuccinimidyl-4-azidobenzoate results in the labeling of two major bands with Mr 158,000 and 100,000 and a minor band with Mr 225,000 as
Markus HosangS, E. M. Shooter
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