Results 71 to 80 of about 60,310 (240)

FGL‐1 Modulates Inter‐Organ Communication by Controlling T Cell Homeostasis during the Onset of Sjögren's Disease

Arthritis &Rheumatology, Accepted Article.
Objective Autoimmunity occurs due to the tactics between pathogenic and regulatory factors in systemic organs. Although inter‐organ communication has been demonstrated in various diseases, the effects of the crosstalk between the immune system and other organs on autoimmune disease is unknown.
Kunihiro Otsuka, Aya Ushio, Ruka Nagao, Shigefumi Matsuzawa, Rieko Arakaki, Kazuki Fukuta, Yasuhiro Mouri, Takaaki Tsunematsu, Naozumi Ishimaru   +8 more
wiley   +1 more source

Arcuate nucleus homeostatic systems reflect blood leptin concentration but not feeding behaviour during scheduled feeding on a high-fat diet in mice [PDF]

, 2017
Acknowledgements T.B. was funded by a CASE studentship from the BBSRC and AstraZeneca. J.B. was a summer student from Bordeaux Sciences Agro and funded by student laboratory experience grant from the British Society of Neuroendocrinology. The authors are
Bake, T., Baron, J., Duncan, J. S., Mercer, J. G., Morgan, D. G. A.   +4 more
core   +1 more source

Cognitive and Cerebral Aging Research in Autism: A Systematic Review on an Emerging Topic

Autism Research, EarlyView.
ABSTRACT Aging in autism is an emerging and under‐explored area of research. This systematic review provides a comprehensive overview of studies on cognitive and both structural and functional cerebral aging in autism. A systematic search of PubMed and APA PsycInfo was conducted up to and including January 2024.
Marine Bessé, Shasha Morel‐Kohlmeyer, Emmanuelle Houy‐Durand, Philippe Prévost, Laurie Tuller, Badiâa Bouazzaoui, Laurence Taconnat, Julia Capdeville, Lucie Angel, Marie Gomot   +9 more
wiley   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

An Efficient Thiol‐ene Mediated Protocol for Thiolated Peptide Synthesis and On‐Resin Diversification

Chemistry – A European Journal, EarlyView.
Herein, a sequential acyl‐thiol‐ene/S‐deacetylation protocol for selective installation of thiol residues onto synthetic peptides, on‐resin, is demonstrated. The hydrothiolation/S‐deacetylation protocol offers a novel synthetic tool for direct peptide conjugation on‐resin and for the preparation of novel disulfide containing neuropeptides displaying ...
Nikita Ostrovitsa, Conor Williams, Konstantin Raabe, Joshua T. McLean, Markus Muttenthaler, Eoin M. Scanlan   +5 more
wiley   +1 more source

Impact of birth weight and gender on early postnatal hypothalamic energy balance regulatory gene expression in the young lamb [PDF]

, 2013
Peer ...
Adam, C. L., Aitken, R. P., Bake, T., Findlay, P. A., Milne, J. S., Wallace, J. M.   +5 more
core   +1 more source

Uncovering New Therapeutic Targets for Amyotrophic Lateral Sclerosis and Neurological Diseases Using Real‐World Data

Clinical Pharmacology &Therapeutics, EarlyView.
Although attractive for relevance to real‐world scenarios, real‐world data (RWD) is typically used for drug repurposing and not therapeutic target discovery. Repurposing studies have identified few effective options in neurological diseases such as the rare disease, amyotrophic lateral sclerosis (ALS), which has no disease‐modifying treatments ...
Mohammadali Alidoost, Jeremy Y. Huang, Georgia Dermentzaki, Anna S. Blazier, Giorgio Gaglia, Timothy R. Hammond, Francesca Frau, Mary Clare McCorry, Dimitry Ofengeim, Jennifer L. Wilson   +9 more
wiley   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Oxytocin Amplifies Negative Response to Ambiguity in Adolescent Females With and Without Eating Disorders

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Eating disorders (ED) typically emerge in adolescence, a critical period for brain development and peer bonding. Interpersonal difficulties—particularly social anxiety—frequently co‐occur with ED. Oxytocin is a neuropeptide that modulates social cognition and linked to prosocial effects.
Victoria Burmester, Emerie Sheridan, Nikita Catalina Julius, Jordan Elliott, Olivia Thackeray, Dasha Nicholls   +5 more
wiley   +1 more source

Discovery of a second SALMFamide gene in the sea urchin Strongylocentrotus purpuratus reveals that L-type and F-type SALMFamide neuropeptides coexist in an echinoderm species [PDF]

, 2010
NOTICE: this is the author’s version of a work that was accepted for publication in MARINE GENOMICS. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may
Bendtsen, Bradbury, Burke, De Bremaeker, De Bremaeker, Díaz-Miranda, Díaz-Miranda, Díaz-Miranda, Elphick, Elphick, Elphick, Elphick, Elphick, Elphick, Elphick, Ghyoot, Matthew L. Rowe, Maurice R. Elphick, Melarange, Melarange, Mita, Mita, Moore, Moss, Newman, Newman, Ohtani, Pesole, Sodergren, Walker, Yun   +30 more
core   +1 more source