Results 81 to 90 of about 27,803 (242)

Comparative Proteomics of Salinity Stress Responses in Fish and Aquatic Invertebrates

PROTEOMICS, EarlyView.
ABSTRACT Fluctuating salinity is symptomatic of climate change challenging aquatic species. The melting of polar ice, rising sea levels, coastal surface and groundwater salinization, and increased evaporation in arid habitats alter salinity worldwide. Moreover, the frequency and intensity of extreme weather events such as rainstorms and floods increase,
Maxime Leprêtre, Jens Hamar, Monica B. Urias, Dietmar Kültz   +3 more
wiley   +1 more source

Ancient grandeur of the vertebrate neuropeptide Y system shown by the coelacanth Latimeria chalumnae

Frontiers in Neuroscience, 2013
The neuropeptide Y (NPY) family receptors and peptides have previously been characterized in several tetrapods, teleost fishes and in a holocephalan cartilaginous fish.
Dan eLarhammar, Christina A Bergqvist
doaj   +1 more source

Proteolytic stabilization of a spider venom peptide results in an orally active bioinsecticide

Pest Management Science, EarlyView.
Selective editing out of an insect gut protease cleavage site renders a spider‐derived insecticidal peptide active by ingestion by insect pests. Abstract BACKGROUND The toxin peptide U1‐AGTX‐Ta1b from the Hobo spider, Eratigena agrestis (Walckenaer, 1802), was studied to determine its potential to serve as a bioinsecticide.
Breck R. Davis, Alexandra M. Haase, Joseph S. Tourtois, Daniel L. Hulbert, Rachel E. Cornell, Brian T. DeVree, Cadence J. Flohrschutz, Lucille M. Bell, Daniel C. Peck, Trang T. Nguyen, Lin Bao, Robert M. Kennedy, Kyle D. Schneider   +12 more
wiley   +1 more source

Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors

Neurobiology of Disease, 2005
Neuropeptide Y (NPY) prominently inhibits epileptic seizures in different animal models. The NPY receptors mediating this effect remain controversial partially due to lack of highly selective agonists and antagonists.
David P.D. Woldbye, Avtandil Nanobashvili, Andreas T. Sørensen, Henriette Husum, Tom G. Bolwig, Gunnar Sørensen, Patrik Ernfors, Merab Kokaia   +7 more
doaj  

Activation of Neuropeptide Y Receptors Modulates Retinal Ganglion Cell Physiology and Exerts Neuroprotective Actions

ASN Neuro, 2015
Neuropeptide Y (NPY) is expressed in mammalian retina but the location and potential modulatory effects of NPY receptor activation remain largely unknown.
João Martins, Filipe Elvas, Dan Brudzewsky, Tânia Martins, Bogdan Kolomiets, Pedro Tralhão, Casper R. Gøtzsche, Cláudia Cavadas, Miguel Castelo-Branco, David P. D. Woldbye, Serge Picaud, Ana R. Santiago, António F. Ambrósio   +12 more
doaj   +1 more source

Developments of Thermosensitive Hydrogel for Maxillofacial Bone Regeneration

Small Science, EarlyView.
Thermosensitive hydrogel with seed cells and growth factors presents a new method for bone regeneration, changing states with temperature and offering fluidity, injectability, and controlled drug release. This article reviews thermosensitive hydrogel's role in angiogenesis, neurogenesis, and osteogenesis in maxillofacial bone regeneration and discusses
Qinrou Zhang, Ying Wu, Jialiang Dai, Zihan Jia, Minjia Zhu, Xinyi Li, Le Xiao, Jingyi Li, Zixiang Dai, Yuxing Bai, Jibin Song, Ke Zhang   +11 more
wiley   +1 more source

Corazonin Stimulates Ecdysteroid Synthesis during the Molting Process of the Swimming Crab, Portunus trituberculatus

Biology
The neuropeptide corazonin (Crz) exerts diverse physiological effects in insects, yet its role in crustaceans remains elusive. The abundant expression of Crz receptor (CrzR) in the Y-organs of several crustaceans suggests a potential involvement of Crz ...
Xi Xie, Jun Zhang, Shisheng Tu, Qi Zhou, Dongfa Zhu   +4 more
doaj   +1 more source

A Smart Functional Microneedle, Tethered with Neuropeptide S and Tissue Inhibitor of Metalloproteinases, Promotes Skin, Vascular, and Nerve Regeneration for Chronic Diabetic Skin Wound Healing

Small Structures, EarlyView.
A smart functional microneedle system, tethered with NPS and TIMP, which not only promotes diabetic wound healing and tissue remodeling at the injury site but also demonstrates the ability to dynamically and responsively release NPS and TIMP as needed, offering a potential therapeutic approach for clinical translation is presented. Increased expression
Yan Gao, Mengdan Cheng, Yiqing Wu, Liangliang Zhang, Bai Xu, Xiaojie Lu   +5 more
wiley   +1 more source

Neuropeptide Y is important for basal and seizure-induced precursor cell proliferation in the hippocampus

Neurobiology of Disease, 2007
We have shown that neuropeptide Y (NPY) regulates neurogenesis in the normal dentate gyrus (DG) via Y1 receptors (Howell, O.W., Scharfman, H.E., Herzog, H., Sundstrom, L.E., Beck-Sickinger, A. and Gray, W.P.
Owain W. Howell, Sharmalene Silva, Helen E. Scharfman, Alexander A. Sosunov, Malik Zaben, Anan Shatya, Guy Mckhann, II, Herbert Herzog, Alexandra Laskowski, William P. Gray   +9 more
doaj  

Acquired narcolepsy secondary to a presumptive hypothalamic hamartoma in a young German wirehaired pointer dog

Veterinary Record Case Reports, EarlyView.
Abstract A 3‐year‐old, male, entire, German wirehaired pointer dog was presented with a 2‐year history of paroxysmal episodes of collapse associated with reduced levels of consciousness. A magnetic resonance imaging study identified a single, ill‐defined, non‐contrast‐enhancing, intra‐axial mass lesion involving the hypothalamus.
Callum Atkins, Tessa V. Procter, Tobias Schwarz, Megan Madden   +3 more
wiley   +1 more source