Results 111 to 120 of about 2,492,882 (302)
Advanced Materials Technologies, EarlyView.This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang +4 more
wiley +1 more source
eLife, 2018 The correct establishment and maintenance of unidirectional Notch signaling are critical for the homeostasis of various stem cell lineages. However, the molecular mechanisms that prevent cell-autonomous ectopic Notch signaling activation and deleterious ...
Bo Li +6 more
doaj +1 more source
Advanced Optical Materials, Volume 13, Issue 8, March 13, 2025.This article presents a hybrid metal‐dielectric metasurface in transmission mode for mid‐infrared (MIR) spectroscopy. Composed of germanium on aluminium cylinders atop a calcium fluoride substrate, the metasurface achieves 80% transmission efficiency at λ = 2.6 µm with a narrow full‐width‐half‐maximum of 0.4 µm.
Amr Soliman +5 more
wiley +1 more source
Vat Photopolymerized HEMA/HEA Hydrogels for Solvent‐Responsive Transparency and Optical Encryption
Advanced Optical Materials, EarlyView.Vat‐photopolymerized HEMA/HEA hydrogels exhibit reversible transparency‐opacity switching via hydration‐induced microphase separation and solvent exchange. The printed materials enable hydration sensing, optical encryption, and information storage, while maintaining high ductility and reversible rheology.
Murad Ali +4 more
wiley +1 more source
YB-1 Acts as a Ligand for Notch-3 Receptors and Modulates Receptor Activation*
Journal of Biological Chemistry, 2009 Y-box (YB) protein-1 is secreted by mesangial and immune cells after cytokine challenge, but extracellular functions are unknown. Here, we demonstrate that extracellular YB-1 associates with outer cell membrane components and interacts with extracellular
T. Rauen +9 more
semanticscholar +1 more source
Prognostic values of Notch receptors in breast cancer
Tumor Biology, 2015 Notch receptors are frequently deregulated in several human malignancies including human breast cancer. Activation of Notch has been reported to cause mammary carcinomas in mice. However, the prognostic value of individual Notch receptors in breast cancer (BC) patients remains elusive. In the current study, we investigated the prognostic value of Notch
Junming, Xu +7 more
openaire +2 more sources
Advanced Science, EarlyView.Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu +23 more
wiley +1 more source
Advanced Science, EarlyView.Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao +4 more
wiley +1 more source
PLoS Computational BiologyThe ubiquitous Notch receptor signalling network is essential for tissue growth and maintenance. Operationally, receptor activity is regulated by two principal, counterposed mechanisms: intercellular Notch transactivation triggered by interactions ...
Daipeng Chen +4 more
doaj +1 more source
Notch Signaling in Neuroendocrine Tumors
Frontiers in Oncology, 2016 Carcinoids and neuroendocrine tumors (NETs) are a heterogeneous group of tumors that arise from the neuroendocrine cells of the GI tract, endocrine pancreas and the respiratory system.
Judy Sue Crabtree +4 more
doaj +1 more source