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[Parathyroid hormone and calcitonin receptors].
Annales d'endocrinologie, 1990Parathyroid hormone and calcitonin are involved in the regulation of calcium metabolism via specific receptors in target organs principally bone and kidney. The pertinent findings in this rapidly evolving area of research are briefly summarized. The receptors for these two hormones have been extensively localised, the transduction of their signal ...
Z, Bouizar, G, Milhaud, M S, Moukhtar
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Parathyroid hormone and parathyroid hormone-related protein receptor update
Molecular and Cellular Endocrinology, 1994Muff R, Born W, Kaufmann M, Fischer JA
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Parathyroid hormone receptor agonists in the management of osteoporosis
Nature Reviews RheumatologyParathyroid hormone (PTH) regulates bone homeostasis. Intermittent exposure to PTH results in bone formation being greater than bone resorption, and this effect has been harnessed through the development of agonists of the PTH and PTH-related protein type 1 receptor (PTH1R) to treat osteoporosis. Teriparatide, an analogue of the first 34 amino acids of
Nicholas Fuggle +35 more
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Parathyroid Hormone and Its Receptors
1998Publisher Summary This chapter discusses the parathyroid hormone and its receptors. Parathyroid hormone (PTH) is synthesized in the parathyroid cells as a pre-pro-hormone comprised of 115 amino acids. The signal peptide of PTH allows translocation of the polypeptide into the secretory vesicles, a property that is shared with most secreted proteins ...
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Receptor, 1994
The receptor for parathyroid hormone (PTH) and PTH-related protein (PTHrP) is a member of a subfamily of G-protein-coupled receptors. This subfamily includes receptors for calcitonin, secretin, vasoactive intestinal polypeptide, glucagon, and related peptides, growth hormone-releasing hormone, and pituitary adenylate cyclase activating peptide.
R A, Nissenson +3 more
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The receptor for parathyroid hormone (PTH) and PTH-related protein (PTHrP) is a member of a subfamily of G-protein-coupled receptors. This subfamily includes receptors for calcitonin, secretin, vasoactive intestinal polypeptide, glucagon, and related peptides, growth hormone-releasing hormone, and pituitary adenylate cyclase activating peptide.
R A, Nissenson +3 more
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Evidence for glomerular receptors for parathyroid hormone
American Journal of Physiology-Renal Physiology, 1978J, Sraer +5 more
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1998
The primary objective of the investigation of the fundamental nature of ligand-receptor interactions is elucidation of the mechanism of ligand recognition and receptor activation. In the case of parathyroid hormone (PTH) and PTH-related protein (PTHrP), which have been well studied from the ligand side of this interaction for many years, the ...
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The primary objective of the investigation of the fundamental nature of ligand-receptor interactions is elucidation of the mechanism of ligand recognition and receptor activation. In the case of parathyroid hormone (PTH) and PTH-related protein (PTHrP), which have been well studied from the ligand side of this interaction for many years, the ...
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Receptors for parathyroid hormone and parathyroid hormone–related protein
2020Thomas J. Gardella +2 more
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