Results 21 to 30 of about 674,548 (295)

Topical prostaglandin analogues and conjunctival inflammation in uveitic glaucoma. [PDF]

, 2012
20.02.14 KB. Ok to add published verson to spiral, OA paper.A pilot study to determine whether topical prostaglandin analogues alter the expression of conjunctival inflammatory markers in patients with uveitic glaucoma.Prospective, single-masked case ...
Sallam, A, Gurbaxani, A, Taylor, SR, Lightman, S   +3 more
core   +1 more source

Multiple Roles of Prostaglandin E2 Receptors in Female Reproduction [PDF]

, 2020
Among prostaglandins, Prostaglandin E2 (PGE2) (PGE2) is considered especially important for decidualization, ovulation, implantation and pregnancy.
Junyan Zhu, Viktoria von Schönfeldt, Lin, Peng, Jeschke, Udo, Ye, Yao, Zhu, Junyan, Yao Ye, Peng Lin, Udo Jeschke, von Schönfeldt, Viktoria   +9 more
core   +1 more source

Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E-2 production [PDF]

, 2004
Levels of prostaglandin E-2 (PGE(2)), a potent inhibitor of fibroblast function, are decreased in the lungs of patients with pulmonary fibrosis, which has been shown to be because of limited expression of cyclooxygenase-2 (COX-2).
McAnulty, R J, Martyn L. Foster, Laurent, G J, Rebecca J. Hodges, R. Gisli Jenkins, Geoffrey J. Bellingan, Jenkins, R G, Bellingan, GJ, Hart, S L, Laurent, GJ, Jenkins, RG, Bottoms, SE, Copeman, DM, Bottoms, S E, Geoffrey J. Laurent, Nanthakumar, C B, Foster, ML, Wheeler-Jones, C P D, Stephen L. Hart, Hodges, RJ, Wheeler-Jones, CPD, Robin J. McAnulty, Bellingan, G J, McAnulty, RJ, Nanthakumar, CB, Inst Child Hlth, Foster, M L, Stephen E. Bottoms, Copeman, D M, Caroline P.D. Wheeler-Jones, Carmel B. Nanthakumar, Hart, SL, Merck Sharp & Dohme, Hodges, R J, UCL, Danielle M. Copeman   +35 more
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Identification of prostaglandin receptors in human ureters

BMC Urology, 2012
Background Prostaglandins play an important role in ureteral obstruction, but the detailed expression profiles of the prostaglandin receptors (PTGER1, PTGER2, PTGER3, PTGER4, PTGFR) remain unknown in the different parts of the human ureter.
Oll Matthias, Baumann Claudia, Behbahani Turang E, Ruecker Alexander von, Müller Stefan C, Ellinger Jörg   +5 more
doaj   +1 more source

Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway [PDF]

, 2007
Prostaglandin E(2) (PGE(2)) has been shown to modulate angiogenesis and tumour progression via the E-series prostanoid-2 (EP2) receptor. Endometrial adenocarcinomas may be exposed to endogenous PGE(2) and exogenous PGE(2), present at high concentration ...
Williams, A R, Battersby, S, Gardner, S, Jabbour, H N, Sales, K J, Anderson, R A   +5 more
core   +1 more source

Prostaglandins and Their Receptors in Eosinophil Function and As Therapeutic Targets

Frontiers in Medicine, 2017
Of the known prostanoid receptors, human eosinophils express the prostaglandin D2 (PGD2) receptors DP1 [also D-type prostanoid (DP)] and DP2 (also chemoattractant receptor homologous molecule, expressed on Th2 cells), the prostaglandin E2 receptors EP2 ...
Miriam Peinhaupt, Eva M. Sturm, Akos Heinemann   +2 more
doaj   +1 more source

The Gαs‐protein‐mediated pathway may be steadily stimulated by prostanoid EP2 receptors, but not by EP4 receptors

FEBS Open Bio, 2022
EP2 and EP4 prostanoid receptors have long been considered to have similar roles, since they are known to couple with Gαs‐protein and activate cAMP‐mediated signaling pathways.
Keijo Fukushima, Kanaho Senoo, Naoki Kurata, John W. Regan, Hiromichi Fujino   +4 more
doaj   +1 more source

Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice [PDF]

, 2007
Cyclooxygenase-2 (COX-2)-dependent prostaglandin (PG) E2 synthesis in the spinal cord plays a major role in the development of inflammatory hyperalgesia and allodynia. Microsomal PGE2 synthase-1 (mPGES-1) isomerizes COX-2-derived PGH2 to PGE2.
Geisslinger, Gerd, Rolf M. Nusing, Gerd Geisslinger, Scholich, Klaus, Angioni, Carlo Federico, Klaus Scholich, Laura Popp, Brenneis, Christian, Ovidiu Coste, Becker, Wiebke, Popp, Laura, Nusing, Rolf M., Coste, Ovidiu, Carlo Angioni, Christian Brenneis, Ronald Schmidt, Wiebke Becker, Schmidt, Ronald   +17 more
core   +1 more source

Prostaglandins in Cancer Cell Adhesion, Migration, and Invasion

International Journal of Cell Biology, 2012
Prostaglandins exert a profound influence over the adhesive, migratory, and invasive behavior of cells during the development and progression of cancer.
David G. Menter, Raymond N. DuBois
doaj   +1 more source

Antinociceptive activity of the S1P-receptor agonist FTY720 [PDF]

, 2008
FTY720 is a novel immunosuppressive drug that inhibits the egress of lymphocytes from secondary lymphoid tissues and thymus. In its phosphorylated form FTY720 is a potent S1P receptor agonist.
Geisslinger, Gerd, Gerd Geisslinger, Scholich, Klaus, Angioni, Carlo Federico, Klaus Scholich, Laura Popp, Sandra Pierre, Brenneis, Christian, Ovidiu Coste, Claudiu Marian, Marian, Claudiu, Popp, Laura, Coste, Ovidiu, Carlo Angioni, Schmidt, Helmut, Christian Brenneis, Pierre, Sandra, Helmut Schmidt   +17 more
core   +1 more source