Results 11 to 20 of about 93,312 (311)
CHIMIA, 2004 Synthesis of novel 7,7-difluoroprostacyclin and 15-deoxy-15,15-difluoro-PGF2? derivatives will be presented. These compounds show high affinity to prostaglandin receptors and potent biological activities.
Yasushi Matsumuraa +3 more
doaj +3 more sources
Respiratory Research, 2023 Background Pulmonary arterial hypertension (PAH), Group 1 pulmonary hypertension (PH), is a type of pulmonary vascular disease characterized by abnormal contraction and remodeling of the pulmonary arterioles, manifested by pulmonary vascular resistance ...
Cheng Zeng +4 more
doaj +1 more source
Pharmacotherapy of glaucoma in terms of evidence-based medicine
Качественная клиническая практика, 2023 Glaucoma is a disease associated with increased intraocular pressure (IOP). Of the pharmacological agents for treating glaucoma, there are drugs of the first (most effective and safe) and second-line treatment. First-line treatment includes prostaglandin
V. N. Fedorov +6 more
doaj +1 more source
Putative role of prostaglandin receptor in intracerebral hemorrhage
Frontiers in Neurology, 2012 Each year, approximately 795,000 people experience a new or recurrent stroke. Of all strokes, 84% are ischemic, 13% are intracerebral hemorrhage (ICH) strokes and 3% are subarachnoid hemorrhage (SAH) strokes.
Shekher eMohan +4 more
doaj +1 more source
Frontiers in Physiology, 2022 Rotaviruses are one of the leading causes of severe dehydrating diarrhoea in infants and children under the age of five. Despite the introduction of vaccines, disease burden remains high in sub-Saharan Africa, with no known anti-viral treatments ...
Willem J. Sander +4 more
doaj +1 more source
Prostaglandins and prostaglandin receptor antagonism in migraine [PDF]
The Journal of Headache and Pain, 2013 Human models of headache may contribute to understanding of prostaglandins' role in migraine pathogenesis. The current thesis investigated the migraine triggering effect of prostaglandin E2 (PGE2) in migraine patients without aura, the efficacy of a novel EP4 receptor antagonist, BGC20-1531, in prevention of PGE2-induced headache and the ability of ...
openaire +2 more sources
Prostaglandin E Positively Modulates Endothelial Progenitor Cell Homeostasis: An Advanced Treatment Modality for Autologous Cell Therapy [PDF]
, 2009 Aims: The mobilization of endothelial progenitor cells (EPC) and their functioning in postnatal neovascularization are tightly regulated. To identify new modulators of EPC homeostasis, we screened biologically active prostaglandin E compounds for their ...
Hermann, Patrick C. +6 more
core +1 more source
BMC Gastroenterology, 2022 Background Aberrations in cyclooxygenase and lipoxygenase (LOX) pathways in non-neoplastic, normal appearing mucosa from patients with colorectal neoplasia (CRN), could hypothetically qualify as predisposing CRN-markers.
Ulrike Ries Feddersen +5 more
doaj +1 more source
Journal of Allergy and Clinical Immunology: Global, 2023 Background: Chronic rhinosinusitis (CRS) can be divided into endotypes by functional or pathophysiologic findings. Objective: The aim of this study was to analyze the expression of cytokines, prostaglandin (PG) synthases, and their receptors related to ...
Aiko Oka, MD +8 more
doaj +1 more source
Topical prostaglandin analogues and conjunctival inflammation in uveitic glaucoma. [PDF]
, 2012 20.02.14 KB. Ok to add published verson to spiral, OA paper.A pilot study to determine whether topical prostaglandin analogues alter the expression of conjunctival inflammatory markers in patients with uveitic glaucoma.Prospective, single-masked case ...
Sallam, A +3 more
core +1 more source