Purinergic receptors in the endocrine and exocrine pancreas [PDF]
Purinergic Signalling, 2007 The pancreas is a complex gland performing both endocrine and exocrine functions. In recent years there has been increasing evidence that both endocrine and exocrine cells possess purinergic receptors, which influence processes such as insulin secretion and epithelial ion transport. Most commonly, these processes have been viewed separately.
openaire +4 more sources
The role of purine metabolites as DAMPs in acute graft-versus-host disease.
Frontiers in Immunology, 2016 Acute graft-versus-host disease (GVHD) causes high mortality in patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT). An early event in the classical pathogenesis of acute GVHD is tissue damage caused by the conditioning ...
Petya Apostolova, Robert Zeiser
doaj +1 more source
The Role of Purinergic Receptors in Cancer-Induced Bone Pain
Journal of Osteoporosis, 2012 Cancer-induced bone pain severely compromises the quality of life of many patients suffering from bone metastasis, as current therapies leave some patients with inadequate pain relief.
Sarah Falk +2 more
doaj +1 more source
ROLE OF PURINERGIC RECEPTORS IN IMMUNE RESPONSE
Journal of microbiology, epidemiology and immunobiology, 2016 Purine receptors are located on immune and somatic cells of animal and human organisms. Summation of signals from purine and TOLL-like receptors takes place on the level of inflammasome formation and results in summation of the first and second signals of innate immunity.
openaire +5 more sources
Binding Selectivity Analysis from Alchemical Receptor Hopping and Swapping Free Energy Calculations [PDF]
arXivWe present receptor hopping and receptor swapping free energy estimation protocols based on the Alchemical Transfer Method (ATM) to model the binding selectivity of a set of ligands to two arbitrary receptors. The receptor hopping protocol, where a ligand is alchemically transferred from one receptor to another in one simulation, directly yields the ...
arxiv
Purinergic signaling in infection and autoimmune disease
Biomedical Journal, 2016 Purinergic signaling plays a key role in inflammatory processes and modulates immune responses against a variety of bacterial and eukaryotic parasites.
Luiz Eduardo Baggio Savio +1 more
doaj
Ectonucleotidases and purinergic receptors in mouse prostate gland. [PDF]
Am J Clin Exp UrolYu J, Sharkey C, Olumi AF, Wang Z.
europepmc +1 more source
Temporal mRNA Expression of Purinergic P2 Receptors in the Brain Following Cerebral Ischemia and Reperfusion: Similarities and Distinct Variations Between Rats and Mice. [PDF]
Int J Mol SciChalla SR +8 more
europepmc +1 more source
Trends in Research on the P2X7 Receptor: A Bibliometric and Visualization Analysis. [PDF]
J Inflamm ResRen C +8 more
europepmc +1 more source
Global trends of purinergic receptors and depression: A bibliometric analysis from 2003 to 2023. [PDF]
World J PsychiatryHuang B +6 more
europepmc +1 more source