Results 111 to 120 of about 577,314 (185)

Temporal Dynamics of Purinergic Receptor Expression in the Lungs of Marek’s Disease (MD) Virus-Infected Chickens Resistant or Susceptible to MD

Viruses
Marek’s disease virus (MDV) is an economic concern for the poultry industry due to its poorly understood pathophysiology. Purinergic receptors (PRs) are potential therapeutic targets for viral infections, including herpesviruses, prompting our ...
Haji Akbar, Keith W. Jarosinski
doaj   +1 more source

Metabotropic regulation of ATP-gated P2X3 receptors

, 2006
Among the ATP-gated channels, the P2X3 subtype is exclusively expressed in nociceptors of dorsal root ganglia (DRG) and trigeminal ganglia, where it plays a major role in enhanced pain sensation observed in chronic pain states.
Chabot-Doré, Anne-Julie.
core  

Ventilatory and carotid body chemoreceptor responses to purinergic P2X receptor antagonists in newborn rats

, 2011
Adenosine triphosphate, acting through purinergic P2X receptors, has been shown to stimulate ventilation and increase carotid body chemoreceptor activity in adult rats.
Aida Bairam, Vincent Joseph, David F. Donnelly, Lalah M. Niane   +3 more
core   +1 more source

Substituted adenine derivatives as novel P2X3 receptor ligands

, 2010
The purinergic P2X3 subtype is an ATP-gated ion channel mainly expressed in pain sensory neurons and thought to mediate nociception especially in conditions like neuropathic pain and migraine.
GIACOBBE D, LAMBERTUCCI, Catia, MARUCCI, Gabriella, DAL BEN, DIEGO, CRISTALLI, Gloria, VOLPINI, Rosaria, PANMAND DS, NISTRI A   +7 more
core   +1 more source

Temporal mRNA Expression of Purinergic P2 Receptors in the Brain Following Cerebral Ischemia and Reperfusion: Similarities and Distinct Variations Between Rats and Mice

Purinergic P2 receptors are crucial in energy utilization and cellular signaling, making them key targets for stroke therapies. This study examines the temporal mRNA expression of all P2 receptors in rats and mice.
Casimir A. Fornal, Isidra M. Baker, Jeffrey D. Klopfenstein, Pavani Unnam, Nidhi Shanthappa, Siva Reddy Challa, Krishna Kumar Veeravalli, Hunter Levingston, Joseph Boston   +8 more
core   +1 more source

ATP-P2X3 Signaling as a Shared Neural Sensitization Pathway in Endometriosis and Irritable Bowel Syndrome: Mechanisms and Therapeutic Implications. [PDF]

Biomedicines
Duong MA, Ramdass PVAK.
europepmc   +1 more source

Electroacupuncture and P2X receptors: purinergic mechanisms in pain modulation : A narrative review with structured evidence mapping. [PDF]

Purinergic Signal
Shaheen R.
europepmc   +1 more source

Pharmacological characterization of purine receptors in bovine fibroblast-like synoviocytes

, 2009
Growing evidence also suggests that extracellular nucleotides, acting through purinergic receptors, play a central role in the regulation of bone and cartilage metabolism.
GESSI, Stefania, CARUSO, Angelo, BOREA, Pier Andrea, VINCENZI, Fabrizio, VARANI, Katia, DE MATTEI, Monica, MERIGHI, Stefania   +6 more
core  

P2X receptors and lipids interact to modulate inflammation. [PDF]

J Lipid Res
Vidal VN, Pereira TC, Teixeira GP, Rocha L, Faria RX.   +4 more
europepmc   +1 more source

Purinergic Signalling in Snakebite Envenomation: Mechanistic Insights, Therapeutic Targets and Future Perspectives. [PDF]

Molecules
Dias DA, Soares MHS, Guimarães RCA.
europepmc   +1 more source