Results 151 to 160 of about 57,506 (257)

The Next Generation of Skin Care: Transforming Retinoid Therapeutics. [PDF]

Cells
Łuczak JW, Palusińska M, Maślińska-Gromadka K, Pietrzak D, Szopiński T, Lewicki S, Schenk T, Szymański Ł.   +7 more
europepmc   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Acute Promyelocytic Leukemia: Pathophysiology, Diagnosis and Clinical Management. [PDF]

Hematol Rep
Abddaoui M, Aghlallou Y, Tlemçani I, Amrani Hassani M.   +3 more
europepmc   +1 more source

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang, Tu Huang, Yi‐hang Hao, Min Zheng, Xin‐hua Liang   +4 more
wiley   +1 more source

Vitamin A toxicity and hepatic pathology: A comprehensive review. [PDF]

World J Hepatol
Pestalardo ML, Bevilacqua CS, Amante MF.
europepmc   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Vitamins A and D and Their Combinations for Breast and Colorectal Cancers: Analysis of the Clinical, Epidemiological, Preclinical and Transcriptomic Data. [PDF]

Pharmaceuticals (Basel)
Lawal TO, Adeniyi BA, Mahady GB.
europepmc   +1 more source

Selective Promotion of Retinal Organoid Attachment and Differentiation by Amine‐ and Hydroxyl‐Modified Surfaces

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
Engineered biomaterial interfaces critically control retinal organoid development. This study examines how surface modifications (amine, hydroxyl, phenyl, and methyl groups) dictate organoid response. Hydrophilic surfaces markedly increase migration and foster retinal ganglion cell differentiation.
Luis Marcos, Charlie Hall, Eric J. Hill, Samantha L. Wilson, Paul Roach   +4 more
wiley   +1 more source

A Novel Tight Junction-Nuclear Receptor Signaling Pathway Regulating Cancer Progression. [PDF]

Pathol Int
Sugimoto K, Chiba H.
europepmc   +1 more source

Retinoic acid receptor (RAR) [PDF]

Science-Business eXchange, 2013
openaire   +1 more source