Results 221 to 230 of about 3,042,168 (292)

Faecalibacterium-derived spermidine mediates the amelioration of fatty liver hemorrhagic syndrome by inulin in laying hens. [PDF]

NPJ Biofilms Microbiomes
Yang X, Li X, Xu D, Feng Y, Guo Y, Hu Y.
europepmc   +1 more source

Protective Effect of Phytic Acid in Cardiovascular Diseases: A Systematic Review

ChemFoodChem, Volume 2, Issue 3, September 2026.
ABSTRACT Cardiovascular diseases (CVDs) are a cluster of ailments that impact the heart and blood vessels and are a primary public health problem of mortality on a global scale. Phytic acid, a dietary constituent frequently present in foods like seeds, has been linked to many pharmacological attributes, including anti‐cancer, antioxidant, anti ...
Marta M. S. de Freitas Almeida, Éverton A. Pereira, Patricia Severino, Cristina Blanco‐Llamero, Sandra L. Santos, Luciana N. Andrade, Ricardo G. Amaral, Eliana B. Souto   +7 more
wiley   +1 more source

Genome-wide analysis reveals ligand-dependent allostery in RARα:RXR-mediated transcriptional regulation. [PDF]

Cell Rep
Hawkins CL, Blaner WS, Fernandez EJ.
europepmc   +1 more source

Comprehensive In Silico Analysis Identifies MSTO1 and LIG1 as Candidate Biomarkers With Diagnostic and Prognostic Relevance in Hepatocellular Carcinoma

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and remains a major cause of cancer‐related mortality worldwide. Its poor clinical outcomes are largely attributed to late‐stage diagnosis and the limited accuracy of currently available diagnostic and prognostic biomarkers.
Jana Hamad, Hussein Fayyad‐Kazan, Fadi Abdel‐Sater   +2 more
wiley   +1 more source

Therapeutic Strategies Targeting the Kidney-Liver-Immune-Heart Network: Circadian and Mechanosensory Pathways in CKD-Associated Cardiac Injury. [PDF]

Int J Mol Sci
Yoshida Y, Fukuoka K, Tanihara T, Hamamura K, Tsuruta A, Koyanagi S, Ohdo S, Matsunaga N.   +7 more
europepmc   +1 more source

Recent Advancements in Drug Delivery Across the Blood–Brain Barrier in Amyotrophic Lateral Sclerosis (ALS)

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Progressive BBB/BSCB dysfunction is increasingly recognized as both a pathological feature and a therapeutic barrier in ALS. Novel delivery technologies and barrier‐restoration strategies may enhance CNS drug exposure, improve the efficacy of disease‐modifying therapies, and advance ALS treatment. ABSTRACT Background Amyotrophic lateral sclerosis (ALS)
Nitesh Sanghai, Kaitlyn Pierce, Nidhi Sharma, Sasha Leggett, Tara Chand Yadav, Pegah Masrori, Devi Atukorallaya, Senthilnathan Palaniyandi, Paul C. Marcogliese, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Preparation of Oral Artesunate-Chitosan Oligosaccharide-Retinoic Acid Copolymer Micelles for Attenuating Hepatic Fibrosis. [PDF]

Pharmaceutics
Lin S, Lu F, Li Q, Zhang K, Zhang W, Chen H, Wang J.   +6 more
europepmc   +1 more source

Fatty Acid‐Binding Protein 5 Potentially Regulates the Proliferation and Metastasis of Uveal Melanoma Cells Through the PI3K/AKT/mTOR Signaling Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Single‐cell and bulk sequencing reveal SPON2, MATK, and FABP5 as prognostic indicators in uveal melanoma. We demonstrated that FABP5 promotes malignancy via the PI3K/AKT/mTOR pathway, as genetic knockdown impairs tumor growth and is rescued by 740Y‐P pharmacological pathway activation. These findings highlight FABP5 maybe as a critical driver of immune
Yue Du, Xue Jiang, Yanyan Zhang, Jianing Ying, Quanyong Yi   +4 more
wiley   +1 more source

The novel retinoid WYC-209 sensitizes multiple myeloma to carfilzomib via epigenetically upregulating ZMYND8. [PDF]

Exp Hematol Oncol
Xu J, Yan J, Zhang H, Dong J, Wu Y, Qian J, Zhao Q, Dong X, Chen B.   +8 more
europepmc   +1 more source

Modulating the Gut‐Microbiota‐Brain Axis in Alzheimer's Disease: Therapeutic Potential of Nutritional and Metabolic Factors

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
This review systematically examines the role of gut microbiota modulation in Alzheimer's disease, focusing on how microbial metabolites and dietary nutrients influence cognitive function and AD pathology, as well as the neuroprotective effects through the gut‐brain axis.
Binyue Xu, Xuhuan Li, Shangling Dong, Zheyuan Zhang, Dong Jin, Guoping Li, Jiesheng Wang   +6 more
wiley   +1 more source