Results 231 to 240 of about 62,881 (303)

DNA From Neutrophil Extracellular Traps Restricts Group 3 Innate Lymphoid Cells Function in Intestinal Epithelial Repair via CCDC25

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
DNA from neutrophil extracellular traps (NET‐DNA) restricts the function of IL‐22‐dependent ILC3s in intestinal defense through coiled‐coil domain containing protein 25 (CCDC25), which hinders the repair of intestinal epithelial cells and promotes the progression of UC.
Bo Xu, Xuezhou Ke, Xueqian Xie, Qi Yi, Chunjing Li, Meng Zhao, Xiangliang Deng, Qing Wang, Hongxu Chen, Rui Xu, Shuiling Cao, Ying Zhu, Lian Zhou, Qimei Wang, Xia Luo   +14 more
wiley   +1 more source

Retinoic acid inhibits the infection of porcine reproductive and respiratory syndrome virus. [PDF]

Front Vet Sci
Guo J, Xiehe S, Wang M, Li T, Zheng Q, Wang A, Xie S, Wan W, Zhao Y, Ma W, Zhao Q, He X, Tang Y.   +12 more
europepmc   +1 more source

Retinoic Acid Informs the Positional Identity of Frontonasal Neural Crest Cells Through Alx Family of Transcription Factors

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Retinoic acid (RA) regulates the positional identity of cranial neural crest cells (CNCCs) through the transcription factors Alx1 and Alx4. Upon receiving RA from the local environment, liganded RAR/RXR heterodimers activate the expression of Alx1 and Alx4, which promote the frontonasal identity of CNCCs and inhibit the first pharyngeal arch identity ...
Shuxuan Wu, Yifan Lu, Yixin Tu, Yuke Xi, Qianxue Wan, Minghui Yue, Huan Liu, Zhaoming Wu   +7 more
wiley   +1 more source

Effects of All-Trans Retinoic Acid on Ovarian Development, Lipid Metabolism, Nutritional Quality, and Gut Microbiota of Female Chinese Mitten Crab During Fattening Period. [PDF]

Int J Mol Sci
Huang P, Gao J, Du J, Zhu H, Cao L, Gao J, Li J, Zheng Y, Xu G, Meng S.   +9 more
europepmc   +1 more source

Antiviral regulator TRIM25 as a prognostic marker of better survival in Merkel cell carcinoma: Association with MCPyV status

International Journal of Cancer, Volume 158, Issue 12, Page 3268-3278, 15 June 2026.
What's new? TRIM25 is known for its role in antiviral immunity and association with poor prognosis in various cancers. This study reveals an association between high TRIM25 expression and Merkel cell polyomavirus positivity in Merkel cell carcinoma.
Klaus W. Fagerstedt, Sami Kilpinen, Johanna Arola, Benjamin Z. Sundqvist, Tom Böhling, Leif C. Andersson, Harri Sihto   +6 more
wiley   +1 more source

Topical Retinoids in Acne Vulgaris and Acne Scars-From Monotherapy to Combining Regimens. [PDF]

Pharmaceuticals (Basel)
Tobiasz A, Jankowska-Konsur A, Nowicka D.   +2 more
europepmc   +1 more source

Retinoic Acid‐Related Orphan Nuclear Receptor Alpha Promotes Cartilage Degeneration in Osteoarthritis by Activating the Wnt/β‐Catenin Pathway

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
During the development of OA, elevated RORα in chondrocytes inhibits β‐catenin degradation in the cytoplasm by activating the Wnt/β‐catenin signaling pathway. When β‐catenin protein accumulates excessively in the cytoplasm, it is transferred to the nucleus and binds to the cytosolic TCF/LEF transcriptional complex, which activates downstream target ...
Ruijue Zhu, Tianwei He, Jiawei Di, Lang Mai, Depeng Wu, Mudan Huang, Yankui Liu, Zhongyu Liu, Liangming Zhang, Lei He   +9 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, Volume 20, Issue 6, Page 1556-1590, June 2026.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

PPARα and RXRα in the regulation of neuronal ceroid lipofuscinosis genes: implications for Batten disease therapy. [PDF]

NeuroImmune Pharm Ther
Chandra S, Pahan K.
europepmc   +1 more source

Positive and Negative Cardiovascular Effects of JAK Inhibitors in Inflammation

ACR Open Rheumatology, Volume 8, Issue 6, June 2026.
Chronic inflammation, characteristic of many autoimmune diseases, such as rheumatoid arthritis (RA), or myeloproliferative neoplasms (MPNs), is an independent driver of accelerated cardiovascular (CV) risk, primarily through proinflammatory cytokines that induce atherosclerosis and endothelial dysfunction.
Aliki Zavoriti, Pierre Miossec
wiley   +1 more source