Results 91 to 100 of about 587,245 (265)

Somatostatin receptor expression in multiple hemangiomas

Discover Oncology
Background Although hemangiomas frequently occur in the skin, mucosa, liver, and brain, they are rarely observed in the abdominal cavity or retroperitoneum.
Benjin Liu, Shangjian Li, Yisi Xu, Xuqi Huang, Xudong Guo, Hanbo Wang, Shaobo Jiang   +6 more
doaj   +1 more source

The Superior Therapeutic Properties of SOM230 Originate from Unique Structural Elements

CHIMIA, 2004
A rational drug design approach involving transposition of functional groups from SRIF into a reduced size cyclohexapeptide template has led to the discovery of SOM230, a novel, stable cyclohexapeptide somatostatin mimic which exhibits unique ...
Ian Lewis, Gisbert Weckbecker, Herbert A. Schmid, Steven W.J. Lamberts, Viktor Boerlin, Joost van der Hoek, Günter Bovermann, Lukas Oberer, Janos Pless, Nagarajan Chandramouli, Wilfried Bauer, Rainer Albert, Christian Bruns   +12 more
doaj   +1 more source

Untersuchungen zur Dimerisierung von Somatostatin-Rezeptoren mit anderen G-Protein-gekoppelten Rezeptoren

, 2004
Heterodimerization, G-Protein-Coupled Receptors, somatostatin receptor, internalization, oligomerization, dimerization, homodimerization, GPCR, desensitization, immunoprecipitationMagdeburg, Univ., Fak.
Laugsch, Magdalena
core  

Anterior cingulate cortex neuron subtypes differentially regulate seizures

Epilepsia, EarlyView.
Abstract Objective This study aimed to investigate the regulatory roles of distinct neuronal subtypes within the anterior cingulate cortex (ACC) in acute seizures and to identify cell type‐specific mechanisms underlying seizure modulation in this region. Methods Acute seizure models were established in mice via pentylenetetrazol injection.
Ziqian Yan, Ting Tang, Kaishan Wang, Bin Fu, Zesheng Li, Mingshan Liu, Hongyi Huang, Yanfeng Yang, Qiang Zheng, Yangmin Zheng, Yongzhi Shan, Yumin Luo, Guoguang Zhao   +12 more
wiley   +1 more source

Scn1a‐mediated developmental regulation of prefrontal cortex plasticity and cognition

Epilepsia, EarlyView.
Abstract Objective The voltage‐gated sodium channel Nav1.1, encoded by Scn1a, is essential for γ‐aminobutyric acid (GABA)ergic function, and its alteration is associated with neurological disorders such as Dravet syndrome and Alzheimer's disease. We previously demonstrated that local Nav1.1 dysfunction in the medial prefrontal cortex (mPFC) during ...
Maurizio S. Riga, Mercedes Pérez‐Fernández, Yuniesky Andrade‐Talavera, Benito Domínguez‐Velasco, Antonio Rodríguez‐Moreno, Manuel Álvarez‐Dolado   +5 more
wiley   +1 more source

Theta oscillations, epileptogenesis, and focal seizures in rodent models of mesial temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Theta oscillations (4–12 Hz) are a prominent network rhythm within hippocampal and parahippocampal structures. Driven by cholinergic and γ‐aminobutyric acidergic inputs originating from the medial septum, physiological theta gates network excitability to control spatial navigation, memory encoding, and sensorimotor integration during specific ...
Maxime Lévesque, Massimo Avoli
wiley   +1 more source

Effects of CP 55,940 — agonist of CB1 cannabinoid receptors on ghrelin and somatostatin producing cells in the rat pancreas

Folia Histochemica et Cytobiologica, 2012
Cannabinoids participate in the modulation of numerous functions in the human organism, increasing the sense of hunger, affecting carbohydrate and lipid metabolism, and controlling systemic energy balance mechanisms.
Alicja Lewandowska, Maria Małgorzata Winnicka, Ewa Arciszewska, Irena Kasacka   +3 more
doaj   +1 more source

Functional characterization of somatostatin receptors expressed on hamster glucagonoma cells

, 1995
We characterized somatostatin receptors expressed in hamster glucagonoma INR1G9 cells and the effects of somatostatin on glucagon secretion, proglucagon gene expression, and the adenosine 3',5'-cyclic monophosphate (cAMP)-dependent signal-transduction ...
H. C. Fehmann, B. Goke, M. Strowski
core   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

The role of somatostatin receptors in breast and pancreatic cancer [PDF]

, 1994
Somatostatin, a hormone which has an inhibitory influence on several physiological processes, is a small peptide consisting of 14 amino-acids, and was first isolated from the hypothalamus of the rat.
Eijck, C.H.J. (Casper) van
core   +1 more source