Results 1 to 10 of about 75,344 (257)

An Update on DOTA-Peptides PET Imaging and Potential Advancements of Radioligand Therapy in Intracranial Meningiomas

open access: yesLife
Meningiomas arise from the meningeal layers covering the central nervous system structures. Although most are benign, meningiomas can still cause neurological morbidity due to the mass effect and compression of the surrounding parenchyma.
Viviana Benfante   +12 more
doaj   +1 more source

A receptor-based analysis of local ecosystems in the human brain. [PDF]

open access: yes, 2017
BackgroundAs a complex system, the brain is a self-organizing entity that depends on local interactions among cells. Its regions (anatomically defined nuclei and areas) can be conceptualized as cellular ecosystems, but the similarity of their functional ...
Janušonis, Skirmantas
core   +1 more source

Contemporary nuclear medicine diagnostics of neuroendocrine tumors [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2015
The new positron emission tomography (PET/CT) methods for neuroendocrine tumors detection are presented and compared with classic, conventional methods. Conventional methods use a gamma scintillation camera for patients with neuroendocrine tumor
Todorović-Tirnanić Mila   +4 more
doaj   +1 more source

Role of cyclic AMP in the control of cell-specific gene expression [PDF]

open access: yes, 1993
Genes have to be expressed in specific cell types at appropriate times of development dependent on external signals. cAMP signaling occurs in all cells, thus raising the question of how this signal transduction pattern is integrated into mechanisms ...
Boshart, Michael   +3 more
core   +1 more source

Current Status of Radiopharmaceuticals for the Theranostics of Neuroendocrine Neoplasms

open access: yesPharmaceuticals, 2017
: Nuclear medicine plays a pivotal role in the management of patients affected by neuroendocrine neoplasms (NENs). Radiolabeled somatostatin receptor analogs are by far the most advanced radiopharmaceuticals for diagnosis and therapy (radiotheranostics ...
Melpomeni Fani   +2 more
doaj   +1 more source

Towards a Radio-guided Surgery with $\beta^{-}$ Decays: Uptake of a somatostatin analogue (DOTATOC) in Meningioma and High Grade Glioma

open access: yes, 2014
A novel radio guided surgery (RGS) technique for cerebral tumors using $\beta^{-}$ radiation is being developed. Checking the availability of a radio-tracer that can deliver a $\beta^{-}$ emitter to the tumor is a fundamental step in the deployment of ...
BELLINI, Fabio   +23 more
core   +1 more source

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion

open access: yesNature Communications, 2019
Impaired glucagon secretion in patients with diabetes causes hypoglycemia. Here the authors show that therapeutic concentrations of insulin inhibit alpha-cell glucagon secretion by stimulating delta-cell insulin receptor and the release of somatostatin ...
Elisa Vergari   +19 more
doaj   +1 more source

False-positive 111 In-pentetreotide Uptake in Gastritis

open access: yesWorld Journal of Nuclear Medicine, 2013
111 In-pentetreotide [ 111 In-octreoscan] is the most widely used radiolabeled somatostatin analog for evaluating neuroendocrine tumor overexpression of somatostatin receptors.
Sharjeel Usmani, Alshaima Alshammari
doaj   +1 more source

SOMATOSTATIN RECEPTORS AS POTENTIALTHERAPEUTIC TARGETS IN THE TREATMENT OF ADVANCED ADRENOCORTICAL CANCER. A CASE REPORT

open access: yesСибирский онкологический журнал, 2018
Background. Adrenocortical cancer (ACC) is a rare malignancy of the adrenal cortex. Therapeutic options for advanced ACC are limited. It is necessary to study new and more effective drug combinations and tumor biological targets. The purpose of the study
A. A. Kolomeytseva   +5 more
doaj   +1 more source

AIP and MEN1 mutations and AIP immunohistochemistry in pituitary adenomas in a tertiary referral center. [PDF]

open access: yes, 2019
Background: Pituitary adenomas have a high disease burden due to tumor growth/ invasion and disordered hormonal secretion. Germline mutations in genes such as MEN1 and AIP are associated with early onset of aggressive pituitary adenomas that can be ...
Cano González, David A.   +2 more
core  

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