Results 11 to 20 of about 39,903 (228)

The role of somatostatin receptor scintigraphy in the diagnosis and follow-up of the pancreatic neuroendocrine neoplasms [PDF]

open access: yesNuclear Technology and Radiation Protection, 2020
The aim of investigation was to assess the role of somatostatin receptor scintigraphy in diagnosis and follow-up of pancreatic neuroendocrine neoplasms.
Šaponjski Jelena M.   +6 more
doaj   +1 more source

Somatostatin receptors in congenital hyperinsulinism: Biology to bedside

open access: yesFrontiers in Endocrinology, 2022
Congenital hyperinsulinism (CHI), although a rare disease, is an important cause of severe hypoglycemia in early infancy and childhood, causing preventable morbidity and mortality.
Mirjam E. van Albada   +4 more
doaj   +1 more source

Role of somatostatin receptor-2 in gentamicin-induced auditory hair cell loss in the Mammalian inner ear. [PDF]

open access: yesPLoS ONE, 2014
Hair cells and spiral ganglion neurons of the mammalian auditory system do not regenerate, and their loss leads to irreversible hearing loss. Aminoglycosides induce auditory hair cell death in vitro, and evidence suggests that phosphatidylinositol-3 ...
Yves Brand   +7 more
doaj   +1 more source

Somatostatin and somatostatin receptors in retinal diseases [PDF]

open access: yesEuropean Journal of Endocrinology, 2000
Somatostatin is a small neuropeptide that is producedin the central nervous system, where it acts as aneurotransmitter. This neuropeptide also has animportant role in the neuroendocrine system as aninhibitor of hormone release, the most strikingexample of which is the inhibition of growth hormonerelease.
van, Hagen PM   +7 more
openaire   +4 more sources

Somatostatin receptor expression in parathyroid neoplasms

open access: yesEndocrine Connections, 2019
Introduction: Parathyroid carcinoma represents a rare cause of primary hyperparathyroidism. Distinguishing carcinoma from the benign tumors underlying primary hyperparathyroidism remains challenging.
Sara Storvall   +6 more
doaj   +1 more source

Evaluation of 99mTc-HYNIC-TOC and 131I-MIBG imaging in diagnosis of pheochromocytoma and paraganglioma [PDF]

open access: yesJichu yixue yu linchuang
Objective To evaluate 99mTc-HYNIC-TOC somatostatin receptor and 131I-MIBG imaging in clinical diag- nostic of pheochromocytoma and paraganglioma (PPGL).
WANG Yu, TONG Anli, ZHOU Yue, ZHANG Wenqian, CUI Yunying, JING Hongli , LI Yuxiu
doaj   +1 more source

Carboxyl-terminal receptor domains control the differential dephosphorylation of somatostatin receptors by protein phosphatase 1 isoforms. [PDF]

open access: yesPLoS ONE, 2014
We have recently identified protein phosphatase 1β (PP1β) as G protein-coupled receptor (GPCR) phosphatase for the sst2 somatostatin receptor using siRNA knockdown screening.
Andreas Lehmann   +4 more
doaj   +1 more source

Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice

open access: yesMolecular Metabolism, 2021
Objective: Maintenance of glucose homeostasis requires the precise regulation of hormone secretion from the endocrine pancreas. Free fatty acid receptor 4 (FFAR4/GPR120) is a G protein-coupled receptor whose activation in islets of Langerhans promotes ...
Marine L. Croze   +11 more
doaj   +1 more source

Somatostatin receptors

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2003
In 1972, Brazeau et al. isolated somatostatin (somatotropin release-inhibiting factor, SRIF), a cyclic polypeptide with two biologically active isoforms (SRIF-14 and SRIF-28). This event prompted the successful quest for SRIF receptors. Then, nearly a quarter of a century later, it was announced that a neuropeptide, to be named cortistatin (CST), had ...
Møller, Lars Neisig   +3 more
openaire   +2 more sources

Expanding the Indication for Novel Theranostic 177Lu-Dotatate Peptide Receptor Radionuclide Therapy: Proof-of-Concept of PRRT in Merkel Cell Cancer

open access: yesCase Reports in Oncology, 2019
The field of theranostics is a new nuclear medicine tool being utilized in the treatment of different types of cancers. It couples receptor-specific based imaging predicting and guiding response to receptor-specific based radionuclide therapies.
Pashtoon M. Kasi   +2 more
doaj   +1 more source

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