The Association Between Somatostatin Receptor Ligand and Vitamin B12 in Patients with Acromegaly
Endocrinology Research and Practice, 2022 Objective: Vitamin B12 deficiency causes hematologic and neuropsychiatric disorders, thus it is important to evaluate it in risky situations. In this study, we aimed to evaluate the association between somatostatin receptor ligands and vitamin B12 in ...
Serdar Şahin +8 more
doaj +2 more sources
Somatostatin receptor expression in parathyroid neoplasms [PDF]
Endocrine Connections, 2019 Introduction: Parathyroid carcinoma represents a rare cause of primary hyperparathyroidism. Distinguishing carcinoma from the benign tumors underlying primary hyperparathyroidism remains challenging.
Sara Storvall +6 more
doaj +2 more sources
Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas. [PDF]
Mol OncolThis study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Taqvi A +6 more
europepmc +2 more sources
Somatostatin receptor imaging of endocrine gastrointestinal tumors
, 1992 Somatostatin receptors are present on various tumors of neuroendocrine origin. We recently developed a technique for the in vivo visualization of somatostatin receptor positive tumors, which offers a powerful alternative to tumor imaging with labeled ...
Van Hagen, P. M. +7 more
core +10 more sources
Role of somatostatin receptor-2 in gentamicin-induced auditory hair cell loss in the Mammalian inner ear. [PDF]
PLoS ONE, 2014 Hair cells and spiral ganglion neurons of the mammalian auditory system do not regenerate, and their loss leads to irreversible hearing loss. Aminoglycosides induce auditory hair cell death in vitro, and evidence suggests that phosphatidylinositol-3 ...
Yves Brand +7 more
doaj +1 more source
Somatostatin subtype-2 receptor-targeted metal-based anticancer complexes [PDF]
, 2012 Conjugates of a dicarba analogue of octreotide, a potent somatostatin agonist whose receptors are overexpressed on tumor cells, with [PtCl 2(dap)] (dap = 1-(carboxylic acid)-1,2-diaminoethane) (3), [(η 6-bip)Os(4-CO 2-pico)Cl] (bip = biphenyl, pico ...
González, Carlos A. +24 more
core +1 more source
Role of Somatostatin Receptor in Pancreatic Neuroendocrine Tumor Development, Diagnosis, and Therapy
Frontiers in Endocrinology, 2021 Pancreatic neuroendocrine tumors (pNETs) are rare and part of the diverse family of neuroendocrine neoplasms (NENs). Somatostatin receptors (SSTRs), which are widely expressed in NENs, are G-protein coupled receptors that can be activated by ...
Yuheng Hu +27 more
doaj +1 more source
Evaluation of 99mTc-HYNIC-TOC and 131I-MIBG imaging in diagnosis of pheochromocytoma and paraganglioma [PDF]
Jichu yixue yu linchuangObjective To evaluate 99mTc-HYNIC-TOC somatostatin receptor and 131I-MIBG imaging in clinical diag- nostic of pheochromocytoma and paraganglioma (PPGL).
WANG Yu, TONG Anli, ZHOU Yue, ZHANG Wenqian, CUI Yunying, JING Hongli , LI Yuxiu
doaj +1 more source
Carboxyl-terminal receptor domains control the differential dephosphorylation of somatostatin receptors by protein phosphatase 1 isoforms. [PDF]
PLoS ONE, 2014 We have recently identified protein phosphatase 1β (PP1β) as G protein-coupled receptor (GPCR) phosphatase for the sst2 somatostatin receptor using siRNA knockdown screening.
Andreas Lehmann +4 more
doaj +1 more source
Molecular Metabolism, 2021 Objective: Maintenance of glucose homeostasis requires the precise regulation of hormone secretion from the endocrine pancreas. Free fatty acid receptor 4 (FFAR4/GPR120) is a G protein-coupled receptor whose activation in islets of Langerhans promotes ...
Marine L. Croze +11 more
doaj +1 more source