Results 21 to 30 of about 39,903 (228)

The Association Between Somatostatin Receptor Ligand and Vitamin B12 in Patients with Acromegaly

open access: yesEndocrinology Research and Practice, 2022
Objective: Vitamin B12 deficiency causes hematologic and neuropsychiatric disorders, thus it is important to evaluate it in risky situations. In this study, we aimed to evaluate the association between somatostatin receptor ligands and vitamin B12 in ...
Serdar Şahin   +8 more
doaj  

Somatostatin and somatostatin receptors in Cushing's disease [PDF]

open access: yesMolecular and Cellular Endocrinology, 2008
Cushing's disease is caused by an ACTH secreting pituitary adenoma. Surgery is the treatment of choice and cure rates between 60 and 90% are reported. For patients in which surgery fails, effective medical treatment options are needed. Somatostatin (SS) receptors (sst) are expressed on normal and tumoral corticotroph cells.
openaire   +4 more sources

The somatostatinergic system in the mammalian cochlea

open access: yesBMC Neuroscience, 2011
Background Little is known about expression and function of the somatostatinergic system in the mammalian cochlea. We have previously shown that somatostatin administration may have a protective effect on gentamicin-induced hair cell loss. In this study,
Kapfhammer Josef P   +5 more
doaj   +1 more source

Peptide receptor radionuclide therapy (PRRT) in radioiodine-refractory thyroid cancer: A case report of significant response to lu177 DOTA-TATE treatment

open access: yesArchives of Endocrinology and Metabolism, 2022
SUMMARY A 59-year-old woman with follicular thyroid carcinoma underwent total thyroidectomy followed by radioiodine treatment. Following treatment, the whole-body scan did not show any abnormal radioiodine uptake. However, during the follow-up, the serum
Saeideh Ataei-Nakhaei   +5 more
doaj   +1 more source

Somatostatin and Somatostatin Receptors in Tumour Biology

open access: yesInternational Journal of Molecular Sciences, 2023
Somatostatin (SST), a growth hormone inhibitory peptide, is expressed in endocrine and non-endocrine tissues, immune cells and the central nervous system (CNS). Post-release from secretory or immune cells, the first most appreciated role that SST exhibits is the antiproliferative effect in target tissue that served as a potential therapeutic ...
openaire   +2 more sources

Somatostatin receptor imaging. the presence of somatostatin receptors in rheumatoid arthritis [PDF]

open access: yesArthritis & Rheumatism, 1994
AbstractObjective. To investigate the in vivo and in vitro expression of somatostatin receptors (SS‐R) on synovial membranes of patients with rheumatoid arthritis (RA).Methods. The joints of 14 consecutive patients with active RA, 4 patients with severe osteoarthritis (OA), and 30 control patients were studied.
P M, Vanhagen   +5 more
openaire   +2 more sources

Expression of somatostatin receptors in hemangioblastomas associated with von Hippel-Lindau disease as a novel diagnostic, therapeutic, and follow-up opportunity: A case report and literature review

open access: yesArchives of Endocrinology and Metabolism
SUMMARY Hemangioblastomas associated with von Hippel-Lindau (VHL) disease are frequently multiple and recur during prolonged follow-up. Currently, no systemic treatment is available for these tumors.
Eloá Pereira Brabo   +4 more
doaj   +1 more source

Molecular imaging for neuroendocrine tumours

open access: yesSwiss Medical Weekly, 2019
Molecular imaging has found numerous applications in oncology as many tumours express or activate tumour specific target molecules or pathways. This relatively new imaging technique results in a better localisation of tumours and improved tumour ...
Kwadwo Antwi   +3 more
doaj   +1 more source

Lutathera®: The First FDA- and EMA-Approved Radiopharmaceutical for Peptide Receptor Radionuclide Therapy

open access: yesPharmaceuticals, 2019
As the first radiopharmaceutical for Peptide Receptor Radionuclide Therapy (PRRT), Lutathera® was approved by the EMA in 2017 and the FDA in 2018 for the treatment of somatostatin receptor (SSTR) positive gastroenteropancreatic neuroendocrine tumors.
Ute Hennrich, Klaus Kopka
doaj   +1 more source

The somatostatin 2A receptor is enriched in migrating neurons during rat and human brain development and stimulates migration and axonal outgrowth. [PDF]

open access: yesPLoS ONE, 2009
The neuropeptide somatostatin has been suggested to play an important role during neuronal development in addition to its established modulatory impact on neuroendocrine, motor and cognitive functions in adults.
Virginia Le Verche   +12 more
doaj   +1 more source

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